The effects of type-I collagen membrane, hydroxyapatite, and platelet-rich plasma on bone regeneration: An experimental study

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dc.authorid0000-0001-6745-3790en_US
dc.authorid0000-0002-2456-7381en_US
dc.contributor.authorGenç, Çiğdem Çetin
dc.contributor.authorGülsün, Belgin
dc.date.accessioned2022-10-03T08:08:48Z
dc.date.available2022-10-03T08:08:48Z
dc.date.issued2021en_US
dc.departmentDicle Üniversitesi, Diş Hekimliği Fakültesi, Ağız-Diş-Çene Hastalıkları ve Cerrahisi Bölümüen_US
dc.description.abstractAim: Various methods have been developed to support bone reconstruction, including the use of autogenous, allogenic, and synthetic bone graft substitutes, membranes, and concentrated supplements. This study aims to compare the effects of collagen membrane, hydroxyapatite, and platelet-rich plasma on the bone regeneration process in a rat model. Methodology: The experiment was conducted with 60 female Wistar albino rats. Subjects were divided randomly into three groups (n: 20). In the first group, the right femurs' defects were left empty (group I), and type-I collagen membrane was applied to the left femurs (group II). TypeI collagen membrane + hydroxyapatite (group III) was applied to the second group, and type-I collagen membrane + hydroxyapatite + platelet-rich plasma (PRP) (group IV) was applied to the third group. Thus, a total of 80 femurs were included in the study, and defects were evaluated histologically on the 10th, 21st, 45th, and 90th days (n: 5). Results: Groups II and III had better osteogenesis scores than group I, whereas group IV had better results than all other groups. Conclusion: In the PRP group, the osteogenesis scores were significantly better than the other groups. However, the healing was almost excellent in all three study groups (groups II, III, and IV) at the end of the experiment.en_US
dc.identifier.citationGenç, Ç. Ç. ve Gülsün, B. (2021). The effects of type-I collagen membrane, hydroxyapatite, and platelet-rich plasma on bone regeneration: An experimental study. International Dental Research, 11(Supplement 1), 96-102.en_US
dc.identifier.doi10.5577/intdentres.2021.vol11.suppl1.16
dc.identifier.endpage102en_US
dc.identifier.issn2146-1767
dc.identifier.issueSupplement 1en_US
dc.identifier.startpage96en_US
dc.identifier.trdizinid516756
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/516756
dc.identifier.urihttps://hdl.handle.net/11468/10595
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/516756
dc.identifier.volume11en_US
dc.indekslendigikaynakTR-Dizin
dc.institutionauthorGülsün, Belgin
dc.language.isoenen_US
dc.publisherUluslararası Diş Araştırmaları Birliğien_US
dc.relation.ispartofInternational Dental Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHydroxyapatiteen_US
dc.subjectType-I collagen membraneen_US
dc.subjectPlatelet-rich plasmaen_US
dc.subjectBone regenerationen_US
dc.subjectOsteogenesisen_US
dc.titleThe effects of type-I collagen membrane, hydroxyapatite, and platelet-rich plasma on bone regeneration: An experimental studyen_US
dc.titleThe effects of type-I collagen membrane, hydroxyapatite, and platelet-rich plasma on bone regeneration: An experimental study
dc.typeArticleen_US

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