Effects of Potentilla fulgens on the changes made in the retinal damage induced by traumatic head injury

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dc.contributor.authorÖzevren, Hüseyin
dc.contributor.authorDeveci, Engin
dc.date.accessioned2024-04-24T17:58:18Z
dc.date.available2024-04-24T17:58:18Z
dc.date.issued2017
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Histoloji ve Embriyoloji Ana Bilim Dalıen_US
dc.description.abstractTraumatic head injury is a leading cause of mortality and morbidity. As a result of head trauma occurring in the retina of the various biochemical, histological and immunohistochemical effects were investigated. Sprague–Dawley rats were subjected to traumatic brain injury with a weight-drop device using 300 g-1 m weight–height impact. Twenty one rats were divided into three groups, as group 1 (vehicle-treated control), group 2 (vehicle-treated trauma) group 3 trauma + Potentilla fulgens (P. Fulgens) 400 mg/ kg/day, i.p.). Distilled water was used as vehicle. All rats were decapitated 5 days after the induction of trauma, and the protective effects of P. Fulgens were evaluated by histological, immunohistochemical and biochemical analyses. Although further studies are necessary to evaluate the time-and dose-dependent neuroprotective effects of P. Fulgens. Depending on whether trauma inhibits apoptosis of photoreceptor cells, ganglion cells, it is thought that the the support against the degeneration of neural connections can be considered. This study indicates that P.Fulgens is potentially useful for the treatment of eye disorders induced by traumatic brain injury.en_US
dc.identifier.citationÖzevren, H. ve Deveci, E. (2017). Effects of Potentilla fulgens on the changes made in the retinal damage induced by traumatic head injury. International Journal of Morphology, 35(3), 840-844.
dc.identifier.doi10.4067/S0717-95022017000300007
dc.identifier.endpage844en_US
dc.identifier.issn0717-9367
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85030215377en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage840en_US
dc.identifier.urihttps://doi.org/10.4067/S0717-95022017000300007
dc.identifier.urihttps://hdl.handle.net/11468/23823
dc.identifier.volume35en_US
dc.identifier.wosWoSidYok
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherUniversidad de la Fronteraen_US
dc.relation.ispartofInternational Journal of Morphologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPotentilla Fulgensen_US
dc.subjectRaten_US
dc.subjectRetinaen_US
dc.subjectTraumatic İnjuryen_US
dc.titleEffects of Potentilla fulgens on the changes made in the retinal damage induced by traumatic head injuryen_US
dc.title.alternativeEfectos de Potentilla Fulgens en los Cambios Producidos Debido al daño Retinal Inducido por Lesión Traumática en la Cabezaen_US
dc.typeArticleen_US

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