An experimental comparison of the effects of calcium sulfate particles and ?-tricalcium phosphate/hydroxyapatite granules on osteogenesis in internal bone cavities

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dc.contributor.authorAtilgan, S.
dc.contributor.authorYaman, F.
dc.contributor.authorYilmaz, U.
dc.contributor.authorGorgun, B.
dc.contributor.authorUnlu, G.
dc.date.accessioned2024-04-24T16:25:01Z
dc.date.available2024-04-24T16:25:01Z
dc.date.issued2007
dc.departmentDicle Üniversitesien_US
dc.description.abstractThis experimental study was carried out to investigate the effect of medical grade calcium sulphate and beta-tricalcium phosphate/hydroxyapatite on new bone formation. Additionally, the study compared these materials for infection, resorption, biocompatibility, immune reaction, fibrotic encapsulation, foreign body reaction and physical attachment. Forty, five-month-old female Wistar Albino rats were used. The 40 rats in the study were divided into 2 groups. Medical grade calcium sulphate particles (SurgiPlaster(R), Bio-Lok International Company) were applied to the rats in group 1 and beta-tricalcium phosphate/hydroxyapatite granules (Camceram(R) Cam Implants by an osteotech, Inc. Company) to those in group 2. On days 10, 21, 30 and 60 postoperatively the femurs were sacrificed and investigated histopathologically. The Mann-Whitney U test was applied to the data obtained as a result of the histopathological analysis of the specimens. No statistically significant differences were observed between the 2 groups. In conclusion, it was determined that both materials resulted in similar fibrous tissue and inflammation responses, that their biocompatibilities were very good and that they did not cause foreign body reaction. Osteogenesis also was observed in the 2 groups after day 21. The effects of calcium sulphate on bone formation were faster than those of beta-tricalcium phosphate/hydroxyapatite. Osteogenesis was not completed to the same extent in the calcium sulphate group as in the beta-tricalcium phosphate/hydroxyapatite group.en_US
dc.identifier.doi10.1080/13102818.2007.10817446
dc.identifier.endpage210en_US
dc.identifier.issn1310-2818
dc.identifier.issn1314-3530
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-34249881615
dc.identifier.scopusqualityQ3
dc.identifier.startpage205en_US
dc.identifier.urihttps://doi.org/10.1080/13102818.2007.10817446
dc.identifier.urihttps://hdl.handle.net/11468/16930
dc.identifier.volume21en_US
dc.identifier.wosWOS:000254704300016
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofBiotechnology & Biotechnological Equipment
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMedical Grade Calcium Sulphate Particlesen_US
dc.subjectBeta-Tricalcium Phosphate/Hydroxyapatite Granularen_US
dc.subjectOsteogenesisen_US
dc.subjectBone Defectsen_US
dc.subjectExperimentalen_US
dc.titleAn experimental comparison of the effects of calcium sulfate particles and ?-tricalcium phosphate/hydroxyapatite granules on osteogenesis in internal bone cavitiesen_US
dc.titleAn experimental comparison of the effects of calcium sulfate particles and ?-tricalcium phosphate/hydroxyapatite granules on osteogenesis in internal bone cavities
dc.typeArticleen_US

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