Identification of free radicals formed in gamma-irradiated acetazolamide using electron paramagnetic resonance spectroscopy
Yükleniyor...
Tarih
2023
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer
Erişim Hakkı
info:eu-repo/semantics/embargoedAccess
Özet
In this study, spectroscopic, dosimetric and stability characteristics of free radicals formed in acetazolamide (ACE) sample as a result of gamma irradiation in the range of 0–15 kGy were determined using electron paramagnetic resonance (EPR) spectroscopy. For this purpose, by interpreting the spectra of the sample in the 0–100 mW microwave power region, it was determined that two different radicals were formed in the sample. The structures formed after irradiation were attributed to CH3OṄ-(radical I) and -OSOṄH (radical II) radicals. The g-values, hyperfine coupling constants and spectrum contribution ratios of these radicals contributing to the experimental spectrum were also calculated. It has been determined that radical II is quite stable both at high temperature and after a long storage period.
Açıklama
Anahtar Kelimeler
Electron resonance, Electron spin resonance spectroscopy, Irradiation
Kaynak
Applied Magnetic Resonance
WoS Q Değeri
N/A
Scopus Q Değeri
Q3
Cilt
54
Sayı
8
Künye
Sütçü, K. ve Osmanoğlu, Y. E. (2023). Identification of free radicals formed in gamma-irradiated acetazolamide using electron paramagnetic resonance spectroscopy. Applied Magnetic Resonance, 54(8), 737-750.
