Demographic and clinicopathological characteristics of nonalcoholic fatty liver disease in the East-Southeastern Anatolia regions in Turkey

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dc.contributor.authorBahçecioǧlu, İbrahim Halil
dc.contributor.authorKoruk, Mehmet
dc.contributor.authorYılmaz, Ömer
dc.contributor.authorBölükbaş, Cengiz
dc.contributor.authorBölükbaş, Füsun
dc.contributor.authorTuncer, İlyas
dc.contributor.authorAtaseven, Hüseyin
dc.contributor.authorYalçın, Kendal
dc.date.accessioned2024-04-24T17:56:30Z
dc.date.available2024-04-24T17:56:30Z
dc.date.issued2005
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalıen_US
dc.description.abstractObjective: To identify the demographic and clinicopathological characteristics of patients diagnosed with non-alcoholic fatty liver disease (NAFLD) and the risk factors for fibrosis based on histopathological findings in East-Southeastern Anatolia regions in Turkey. Subjects and Methods: The study included a total of 93 patients diagnosed with NAFLD from 5 different centers. Histopathological findings were evaluated by dividing them into four categories using Matteoni classifications. Cases with fibrosis were further evaluated using Brunt classifications. Results: The patients with a nonalcoholic fatty liver were in the 3rd and 4th decade age groups. The mean age was 38 years, 76% of the patients were male, 85% were overweight, 37% were obese, 18% had type 2 diabetes mellitus, and 80.6% had hyperlipidemia. A multiple regression analysis showed that age, type 2 diabetes mellitus, and aspartate aminotransferase (AST) levels were linked with the severity of the disease. Of the 93 patients, 55 (59.1%) had fibrosis, of which 10.8% were classified as severe. The severity of fibrosis was significantly higher in obese patients. Conclusions: The risk factors for severity of NAFLD included advanced age, type 2 diabetes mellitus and serum AST level, while the risk factor for the severity of fibrosis was obesity.en_US
dc.identifier.citationBahçecioǧlu, İ. H., Koruk, M., Yılmaz, Ö., Bölükbaş, C., Bölükbaş, F., Tuncer, İ. ve diğerleri. (2005). Demographic and clinicopathological characteristics of nonalcoholic fatty liver disease in the East-Southeastern Anatolia regions in Turkey. Medical Principles and Practice, 15(1), 62-68.
dc.identifier.doi10.1159/000089388
dc.identifier.endpage68en_US
dc.identifier.issn1011-7571
dc.identifier.issue1en_US
dc.identifier.pmid16340230
dc.identifier.scopus2-s2.0-29044436244
dc.identifier.scopusqualityQ1
dc.identifier.startpage62en_US
dc.identifier.urihttps://doi.org/10.1159/000089388
dc.identifier.urihttps://hdl.handle.net/11468/23548
dc.identifier.volume15en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.relation.ispartofMedical Principles and Practice
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectFibrosisen_US
dc.subjectHistopathologyen_US
dc.subjectNonalcoholic fatty liver diseaseen_US
dc.titleDemographic and clinicopathological characteristics of nonalcoholic fatty liver disease in the East-Southeastern Anatolia regions in Turkeyen_US
dc.titleDemographic and clinicopathological characteristics of nonalcoholic fatty liver disease in the East-Southeastern Anatolia regions in Turkey
dc.typeArticleen_US

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