CAN HISTOLOGICAL AND HISTOMORPHOMETRICAL CHANGES BE INDUCED IN RAT MANDIBULAR CONDYLE FOLLOWING OVARIECTOMY AND LONG-TERM EXTREMELY LOW FREQUENCY MAGNETIC FIELD EXPOSURE?

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dc.contributor.authorUlku, Sabiha Zelal
dc.contributor.authorAkdag, Mehmet Zulkuf
dc.contributor.authorYavuz, Izzet
dc.contributor.authorCelik, Mustafa Salih
dc.contributor.authorKetani, Muzaffer Aydin
dc.date.accessioned2024-04-24T17:27:41Z
dc.date.available2024-04-24T17:27:41Z
dc.date.issued2012
dc.departmentDicle Üniversitesien_US
dc.description.abstractThe quantity and quality of maxillary and mandibular bone have long been a focus of attention for dental clinicians. The mandibular condyle is a major growth site and plays an important role during mandibular growth. The aim of the present study was to evaluate the effects of long-term extremely low frequency magnetic field (ELF-MF) and hormonal changes produced by bilateral ovariectomy on the histologic and histomorphometric structure of rat mandibular condyle. Forty mature female Sprague-Dawley rats were randomly divided into four different groups (n = 10): control (Cnt), ovariectomy (OVX), ELF-MF exposure (ELF-MF), ELF-MF exposure with OVX application (ELF-MF+OVX). All rats were subjected to bilateral ovariectomy except those in Cnt and ELF-MF groups. ELF-MF and ELF-MF+OVX groups were exposed to 1.5 mT ELF-MF during 6 months, 4 h a day After all applications, left condyle of rats were removed to examine histopathologically. Some histopathologic changes were observed, such as irregular appearance in bone marrow cavities in rat condyles of OVX, ELF-MF and ELF-MF+OVX groups. Some disorders in transition from hypertrophic field to ossification layer and irregular appearance in calcification were determined in OVX group. In OVX+ELF-MF and ELF-MF groups, there was significant disruption and latency in calcification and ossification areas. However, no significant differences were found in the thickness of the condylar cartilage layer between groups (P > 0.05). It was suggested that long-term ELF-MF exposure and ELF-MF exposure with ovariectomy application can affect the histologic structure of rats' condyle. Consequently, it was concluded that long-term ELF-MF exposure and ovariectomy application can induce histopathological changes in the structure of the condyle and ELF-MF exposure cannot alter ovariectomy-induced changes.en_US
dc.identifier.doi10.5504/BBEQ.2012.0014
dc.identifier.endpage2920en_US
dc.identifier.issn1310-2818
dc.identifier.issn1314-3530
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-84862519856
dc.identifier.scopusqualityQ3
dc.identifier.startpage2916en_US
dc.identifier.urihttps://doi.org/10.5504/BBEQ.2012.0014
dc.identifier.urihttps://hdl.handle.net/11468/20140
dc.identifier.volume26en_US
dc.identifier.wosWOS:000303225600017
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofBiotechnology & Biotechnological Equipment
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectElf Magnetic Fielden_US
dc.subjectOvariectomyen_US
dc.subjectMandibular Condyleen_US
dc.subjectRatsen_US
dc.titleCAN HISTOLOGICAL AND HISTOMORPHOMETRICAL CHANGES BE INDUCED IN RAT MANDIBULAR CONDYLE FOLLOWING OVARIECTOMY AND LONG-TERM EXTREMELY LOW FREQUENCY MAGNETIC FIELD EXPOSURE?en_US
dc.titleCAN HISTOLOGICAL AND HISTOMORPHOMETRICAL CHANGES BE INDUCED IN RAT MANDIBULAR CONDYLE FOLLOWING OVARIECTOMY AND LONG-TERM EXTREMELY LOW FREQUENCY MAGNETIC FIELD EXPOSURE?
dc.typeArticleen_US

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