A multicenter retrospective analysis on therapeutic plasma exchange in immune thrombocytopenic purpura

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dc.contributor.authorBasturk, Abdulkadir
dc.contributor.authorSayin, Serhat
dc.contributor.authorErkurt, Mehmet Ali
dc.contributor.authorSarici, Ahmet
dc.contributor.authorEkinci, Omer
dc.contributor.authorKum, Asli
dc.contributor.authorBerber, Ilhami
dc.date.accessioned2024-04-24T16:18:31Z
dc.date.available2024-04-24T16:18:31Z
dc.date.issued2021
dc.departmentDicle Üniversitesien_US
dc.description.abstractImmune Thrombocytopenia (ITP) is an autoimmune disease characterized by thrombocytopenia and skin and mucosal bleeding. In patients with an indication for treatment, corticosteroids, intravenous immunoglobulin (IVIg) and anti-D are recommended as the first line, while splenectomy, thrombopoietin receptor agonists or rituximab are recommended second line options. Approximately 10 % of adult patients with ITP fall into the chronic refractory ITP group. Therapeutic plasma exchange (TPE) has generally been tested in patients with refractory ITP, who have failed to respond to conventional treatments, in case of bleeding or prior to surgical interventions. It has been stated that elimination of the antibodies that are held responsible in the pathogenesis of the disease has an effective role in the treatment. In this article, we present the results of 17 patients, who underwent TPE for refractory ITP, together with the literature data.en_US
dc.identifier.doi10.1016/j.transci.2021.103246
dc.identifier.issn1473-0502
dc.identifier.issn1878-1683
dc.identifier.issue5en_US
dc.identifier.pmid34419359
dc.identifier.urihttps://doi.org/10.1016/j.transci.2021.103246
dc.identifier.urihttps://hdl.handle.net/11468/16147
dc.identifier.volume60en_US
dc.identifier.wosWOS:000697004600013
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherPergamon-Elsevier Science Ltden_US
dc.relation.ispartofTransfusion and Apheresis Science
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectImmune Thrombocytopeniaen_US
dc.subjectRefractoryen_US
dc.subjectTherapeutic Plasma Exchangeen_US
dc.subjectAnalysisen_US
dc.titleA multicenter retrospective analysis on therapeutic plasma exchange in immune thrombocytopenic purpuraen_US
dc.titleA multicenter retrospective analysis on therapeutic plasma exchange in immune thrombocytopenic purpura
dc.typeArticleen_US

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