2004-2006 yıllarında izole edilen Acinetobacter baumannii suşlarında antibiyotik direnci

Çal›flmada 2004-2006 y›llar›nda infeksiyon etkeni olarak izole edilen Acinetobacter baumannii sufllar›n›n antibiyotik dirençlerinin belirlenmesi amaçlanm›flt›r. ‹zole edilen sufllarda M‹K de¤erlerine göre 2004 ve 2006 y›llar›nda meropeneme % 7 ve % 25, amikasine % 59 ve % 59, seftazidime % 80 ve % 88, siprofloksasine % 54 ve % 82, sefepime % 83 ve % 87, gentamisine % 78 ve % 87, ko-trimoksazole % 73 ve % 78 oran›nda direnç tespit edilmifltir. Meropenem ve siprofloksasinde 2004’e göre 2006’da direnç art›fl› anlaml› bulunmufltur. ‹mipenem direnci ise sadece 2006 y›l› için de¤erlendirilmifl ve oran % 24 olarak bulunmufltur. A.baumannii sufllar›na en etkili antibiyotiklerin imipenem ve meropenem oldu¤u saptanm›flt›r.

The aim of this study is to detect the antibiotic resistance of Acinetobacter baumannii strains isolated from clinical specimens in years 2004-2006 as infection agents. According to the MIC values, the rates of resistant strains in 2004 and 2006 were as follows; 7 % and 25 % to meropenem, 59 % and 59 % to amikacin, 80 % and 88 % to ceftazidime, 54 % and 82 % to ciprofloxacin, 83 % and 87 % to cefepime, 78 % and 87 % to gentamicin, and 73 % and 78 % to co-trimoxazole, respectively. The increase in resistance rates for meropenem and ciprofloxacin in 2006 was found significant. The imipenem resistance was only evaluated for 2006 and the rate was found to be 24 %. The most efficient antibiotics were found as imipenem and meropenem for A.baumannii strains.