Retrospective evaluation and one year monitoring of 58 patients according to neural tube defect etiology

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dc.contributor.authorArpa, Abdurrahman
dc.contributor.authorÖztürk, Pınar Aydın
dc.contributor.authorAsena, Muhammed
dc.contributor.authorAktaş, Ulaş
dc.contributor.authorGüler, Tuğba Morali
dc.date.accessioned2024-04-24T17:58:20Z
dc.date.available2024-04-24T17:58:20Z
dc.date.issued2024
dc.departmentDicle Üniversitesien_US
dc.description.abstractAim: Neural tube defects (NTDs) are a group of diseases caused by genetic and environmental factors; however, their complete etiology remains unknown. Folate deficiency, medications, maternal diseases and a low socioeconomic status, as well as genetic factors, are known risk factors for NTD. The purpose of this study was to determine possible etiologic factors of NTD and to evaluate patients after 1 year of monitoring. Methods: We retrospectively analyzed 58 patients who were operated as neonates at our hospital in 2017. Results: Of 58 patients, 60.3% were female and 39.7% were male. The frequency of birth abnormalities was higher in mothers aged > 35 years. Overall, 56.9% of the pregnancies occurred during the hot months and 43.1% during the cold months according to the neurulation period. Encephalocele was detected in 3.4%, myelomeningocele in 31% and myeloschisis in 63.8% of patients. Of all patients, 60.3% were diagnosed with hydrocephalus either at birth or at a 1-year follow-up, and they wore a shunt. Conclusion: The results indicate that NTD incidence is higher among females and exerts a high myeloschisis frequency. Other risk factors include kin marriage, family history of NTD, a maternal age outside the range of 19–34 years and mothers with 0 Rh+ blood type. Furthermore, there was a high incidence of abnormalities in the urinary and other systems, which should be considered during patients’ monitoring and surgery. Additionally, there may be a correlation between a sac size and hydrocephalus as well as between myeloschisis and a risk of hydrocephalus.en_US
dc.identifier.citationArpa, A., Öztürk, P. A., Asena, M., Aktaş, U. ve Güler, T. M. (2024). Retrospective evaluation and one year monitoring of 58 patients according to neural tube defect etiology. Ceska a Slovenska Neurologie a Neurochirurgie, 87(1), 48-52.
dc.identifier.doi10.48095/cccsnn202448
dc.identifier.endpage52en_US
dc.identifier.issn1210-7859
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85188611451en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage48en_US
dc.identifier.urihttps://doi.org/10.48095/cccsnn202448
dc.identifier.urihttps://hdl.handle.net/11468/23852
dc.identifier.volume87en_US
dc.identifier.wosWOS:001263642100005en_US
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherCzech Medical Association J.E. Purkyneen_US
dc.relation.ispartofCeska a Slovenska Neurologie a Neurochirurgieen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHydrocephalusen_US
dc.subjectNeural tube defecten_US
dc.subjectSpina bifidaen_US
dc.titleRetrospective evaluation and one year monitoring of 58 patients according to neural tube defect etiologyen_US
dc.title.alternativeRetrospektivní hodnocení a jednoleté sledování 58 pacient? podle etiologie defektu nervové trubiceen_US
dc.typeArticleen_US

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