Efficiency of treatment of long period pegile-interferon in delta hepatitis

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dc.contributor.authorTekin R.
dc.contributor.authorAyaz C.
dc.contributor.authorÇelen M.K.
dc.date.accessioned2024-04-24T17:58:56Z
dc.date.available2024-04-24T17:58:56Z
dc.date.issued2010
dc.departmentDicle Üniversitesien_US
dc.description.abstractDespite all, it's treatment is still uneffective and has few alternatives. There is no more alternative utility treatment way except interferons in hepatitis delta infection. Twenty one naive patients with chronic hepatitis delta were included to this study. The patients were arranged in two groups. First group contains 11 patients who received PEG-IFN-?-2a for 1 year, and second group contains 10 patients who received PEG-IFN-?-2a for 2 years. We ascertained the effects of the treatment on liver function tests, virologic parameters and changes in liver histopathology. HDV-RNA became negative in 2 patients in first group (18%), and 3 patients in second group (30%). This negativeness continued up to 24th week after treatment had ended both of two groups. Post-treatment serological response, biochemical response, and histological response was no significant differences in statistically (p>0.05). In conclusion, PEG-IFN-?-2a treatment for two years has more superiority than one year treatment. Limitted number of patients in our study suggests other studies and treatment options for large series in the future.en_US
dc.identifier.endpage209en_US
dc.identifier.issn1306-8814
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-79851496850en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage206en_US
dc.identifier.urihttps://hdl.handle.net/11468/24165
dc.identifier.volume4en_US
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.relation.ispartofAnatolian Journal of Clinical Investigationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHdven_US
dc.subjectPeginterferonen_US
dc.subjectTreatmenten_US
dc.titleEfficiency of treatment of long period pegile-interferon in delta hepatitisen_US
dc.title.alternativeDelta hepati?ti?nde uzun süreli? pegi?le-i?nterferon tedavi?si?ni?n etki?nli??i?en_US
dc.typeArticleen_US

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