Coagulation parameters in the patients with Fournier's gangrene

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dc.contributor.authorŞahin, Hayrettin
dc.contributor.authorAflay, Uǧur
dc.contributor.authorKılınç, Nihal
dc.contributor.authorBircan, Mehmet Kamuran
dc.contributor.orcid0000-0003-3311-3530
dc.date.accessioned2024-04-24T17:56:05Z
dc.date.available2024-04-24T17:56:05Z
dc.date.issued2005
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Üroloji Ana Bilim Dalıen_US
dc.description.abstractAim: In this prospective study, we aimed to determine the coagulation parameters in the patients with Fournier's gangrene. Methods: The study group is consisted of 12 consecutive Fournier's gangrene patients (11 men and 1 woman) and control group is consisted of patients with Periurethral abscess (n=2), Scrotal abscess (n=4) and Epididimorchitis (n=4). Fibrinogen, protein C, protein S, antithrombin III, lupus anticoagulant, cardiolipin IgG and IgM, prothrombin time-international normalized ratio, activated partial thromboplastin time, platelet count, proaccelerin, antihemophilic globulin (FVIII), albumin, and calcium were evaluated in all subjects. Tissue specimens were taken from Fournier's gangrene patients. These specimens were tested for arterial and venous thrombosis using light microscopy. Results: All of the patients with Fournier's gangrene had both arterial and venous thrombosis in tissue specimens. The levels of fibrinogen and FVIII were high, the level of protein C was low in 12 patients. Lupus Anticoagulant was positive 11 of 12 patients. Conclusions: According to our findings, we think that some coagulation parameters (FVIII, Lupus anticoagulant, protein C, fibrinogen) may be diagnostic for Fournier's gangrene.en_US
dc.identifier.citationŞahin, H., Aflay, U., Kılınç, N. ve Bircan, M. K. (2005). Coagulation parameters in the patients with Fournier's gangrene. International Urology and Nephrology, 37(4), 733-737.
dc.identifier.doi10.1007/s11255-005-8437-y
dc.identifier.endpage737en_US
dc.identifier.issn0301-1623
dc.identifier.issue4en_US
dc.identifier.pmid16362590
dc.identifier.scopus2-s2.0-31144454866
dc.identifier.scopusqualityQ2
dc.identifier.startpage733en_US
dc.identifier.urihttps://doi.org/10.1007/s11255-005-8437-y
dc.identifier.urihttps://hdl.handle.net/11468/23270
dc.identifier.urihttps://link.springer.com/article/10.1007/s11255-005-8437-y
dc.identifier.volume37en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSpringer Netherlandsen_US
dc.relation.ispartofInternational Urology and Nephrology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCoagulationen_US
dc.subjectFibrinogenen_US
dc.subjectFournier's gangreneen_US
dc.subjectFvıııen_US
dc.subjectLupus anticoagulanten_US
dc.subjectProtein Cen_US
dc.titleCoagulation parameters in the patients with Fournier's gangreneen_US
dc.titleCoagulation parameters in the patients with Fournier's gangrene
dc.typeArticleen_US

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