Eritema nodozum: 33 hastanın klinik ve demografik özellikleri
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Tarih
2015
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Dicle Üniversitesi
Erişim Hakkı
Attribution-NonCommercial 3.0 United States
info:eu-repo/semantics/closedAccess
info:eu-repo/semantics/closedAccess
Özet
Giriş: Kliniğimizde eritema nodozum tanısıyla takip ve
tedavileri yapılan hastaların demografik ve klinik özelliklerinin
belirlenmesi, etiyolojik faktörlerin araştırılması, laboratuvar
bulguları ve tedavi rejimlerinin değerlendirilmesi
amaçlanmıştır.
Yöntemler: Üniversitemiz Dermatoloji Kliniği’nde 2008-
2014 yılları arasında yatırılıp takip edilen, klinik ve histopatolojik
olarak eritema nodozum tanısı almış 33 hasta
retrospektif olarak değerlendirildi.
Bulgular: Çalışmaya alınan hastaların yaşları 11 ile 69
yıl arasında olup ortalama yaş 40,57±13,98 yıl olarak
bulundu. Hastalar en çok 30-39 yaş aralığında (%33,3)
saptandı. Hastaların 29’u (%87,9) kadın, 4’ü (%12,1)
erkek idi. Lezyonların en sık yerleşim yeri %54,5 ile alt
ekstremitelerde bulundu. Etiyolojide en sık %30,3 ile enfeksiyonlar
(Üst solunum yolu ve idrar yolu enfeksiyonları)
görülürken bunu ilaçlar (%12,1), gebelik (%6,1), Behçet
hastalığı (%6,1) ve Sarkoidoz (%3,1) takip ediyordu. Ortalama
hastalık süresi 12,60 gün olarak bulundu. Hastaların
%72,7’si ilk atak şeklinde başvurmuştu. Ortalama
hastanede yatış süresi 8,93 gün olarak bulundu.
Sonuç: Eritema nodozumda etiyoloji ülkeden ülkeye
farklılık göstermekte olup çalışmamızda en sık idiopatik
(%42,4) olarak bulundu. Ancak tüm çalışmalarda etiyolojik
faktörler benzer olup sadece sıralamada farklılık gösteriyordu.
Klinik, laboratuvar, histopatolojik bulgular ve tedavi
uygulamaları arasında belirgin bir farklılık görülmedi.
Objective: In this study our aim was to determine demographic and clinical features, etiological factors, laboratory findings and treatment regimens of patients who were diagnosed and treated with erythema nodosum. Methods: Thirty-three patients who were clinical and histopathological diagnosed as erythema nodosum in dermatology clinic of our university, dated between 2008 and 2014, were evaluated retrospectively. Results: The study population consisted of 29 (87.9%) female and 4 (12.1%) male, with a mean age of 40.57±13.98 years (range, 11-69 years). Most patients were found in the 30-39 age range. The most frequent localization of lesions was found in the lower extremities (54.5%). Infections (30.3%) were the most common identified etiologic factors followed by drugs (12.1%), pregnancy (6.1%), Behcet’s disease (6.1%) and sarcoidosis (3.1%). The mean duration of disease was 12.60 days. 72.7% of patients were admitted as the first episode. The mean hospitalization time was 8.93 days. Conclusion: The etiology of erythema nodosum varies from country to country. The most common etiological factor was found idiopathic (42.4%) in our study. However, etiologic factors are similar in all studies, only showed differences in the rankings. No showed significant difference between clinical, laboratory, histopathological findings and treatment.
Objective: In this study our aim was to determine demographic and clinical features, etiological factors, laboratory findings and treatment regimens of patients who were diagnosed and treated with erythema nodosum. Methods: Thirty-three patients who were clinical and histopathological diagnosed as erythema nodosum in dermatology clinic of our university, dated between 2008 and 2014, were evaluated retrospectively. Results: The study population consisted of 29 (87.9%) female and 4 (12.1%) male, with a mean age of 40.57±13.98 years (range, 11-69 years). Most patients were found in the 30-39 age range. The most frequent localization of lesions was found in the lower extremities (54.5%). Infections (30.3%) were the most common identified etiologic factors followed by drugs (12.1%), pregnancy (6.1%), Behcet’s disease (6.1%) and sarcoidosis (3.1%). The mean duration of disease was 12.60 days. 72.7% of patients were admitted as the first episode. The mean hospitalization time was 8.93 days. Conclusion: The etiology of erythema nodosum varies from country to country. The most common etiological factor was found idiopathic (42.4%) in our study. However, etiologic factors are similar in all studies, only showed differences in the rankings. No showed significant difference between clinical, laboratory, histopathological findings and treatment.
Açıklama
Anahtar Kelimeler
Eritema nodozum, Erythema nodosum, Etiyoloji, Etiology, Klinik, Clinic, Demografi, Demographic, Tedavi, Treatment
Kaynak
Dicle Tıp Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
42
Sayı
1
Künye
Sula B., Arıca M. (2015) "Eritema nodozum: 33 hastanın klinik ve demografik özellikleri", Dicle Tıp Dergisi, 42 (1), 46-50.