Platelet aggregation in type two diabetes mellitus and its relationship with lipoprotein levels

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dc.contributor.authorSermet, A
dc.contributor.authorKocyigit, Y
dc.contributor.authorAtmaca, M
dc.contributor.authorKelle, M
dc.contributor.authorDiken, H
dc.date.accessioned2024-04-24T17:37:46Z
dc.date.available2024-04-24T17:37:46Z
dc.date.issued1998
dc.departmentDicle Üniversitesien_US
dc.description.abstractThe relationship between in vitro platelet aggregation and plasma lipoprotein concentrations, in 32 type hive non-insulin dependent diabetes mellitus (NIDDM) patients and 32 healthy subjects, was studied. An increase in the fasting plasma glucose and serum fructosamine concentrations in NIDDM patients was determined. No significant difference was found between platelet counts of the diabetic and control groups, but platelet aggregation induced by adenosine diphosphate (ADP), epinephrine and collagen were significantly higher than in healthy controls. Plasma total cholesterol, low density lipoprotein cholesterol (LDL-C) and triglyceride levels were significantly higher, and the plasma high density lipoprotein cholesterol (HDL-C) level was significantly lower than the controls. In vitro platelet aggregation induced by ADP, epinephrine and collagen correlated positively with LDL-C levels and the LDL-C/HDL-C ratio in both groups, and negatively with HDL-C levels in the diabetic group.en_US
dc.identifier.endpage92en_US
dc.identifier.issn0961-088X
dc.identifier.issue226en_US
dc.identifier.scopus2-s2.0-3042910991
dc.identifier.scopusqualityN/A
dc.identifier.startpage85en_US
dc.identifier.urihttps://hdl.handle.net/11468/21173
dc.identifier.volume57en_US
dc.identifier.wosWOS:000074892400003
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherFaculty Pressen_US
dc.relation.ispartofBiomedical Letters
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPlatelet Aggregationen_US
dc.subjectDiabetes Mellitusen_US
dc.subjectLipoproteinen_US
dc.titlePlatelet aggregation in type two diabetes mellitus and its relationship with lipoprotein levelsen_US
dc.titlePlatelet aggregation in type two diabetes mellitus and its relationship with lipoprotein levels
dc.typeArticleen_US

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