Cryptococcus liquefaciens meningitis in a patient with T cell non Hodgin lymphoma

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dc.contributor.authorOzcan, Nida
dc.contributor.authorDal, Tuba
dc.contributor.authorAkpolat, Nezahat
dc.contributor.authorDurmaz, Riza
dc.contributor.authorYakut, Salim
dc.contributor.authorZeybek, Hasan
dc.contributor.authorGul, Kadri
dc.date.accessioned2024-04-24T17:18:49Z
dc.date.available2024-04-24T17:18:49Z
dc.date.issued2019
dc.departmentDicle Üniversitesien_US
dc.description.abstractInvasive fungal cryptococcosis including meningitidis is a growing threat to immunocompromised patients. Cryptococcus neoformans and Cryptococcus gattii are the main agents of human cryptococcosis. In recent years, there has been an increased incidence of opportunistic infections caused by other species, such as C. liquefaciens. In this study, we presented a meningitis case report caused by Cryptococcus liquefaciens in a 12 years old girl with T cell NHL (Non Hodgin lymphoma). A 12-year-old female patient with a diagnosis of T-NHL (T cell Non-Hodgkin's lymphoma) under the chemotherapy was hospitalized in Hematology Clinic with the complaints of fever and occasional headache for three days. The yeast colonies were isolated from cerebrospinal fluid material (CSF). MALDI-TOF MS (Matriks assisted laser desorption ionization time of flight mass spectrometry, Bruker Daltonics, USA) and Nested PCR (polymerase chain reaction) were used to identify the yeast. Isolated yeast is identified as Cryptococcus liquefaciens by MALDI-TOF MS and Nested PCR. In conclusion, C. liquefaciens can be a causative agent of menigitidis in cases with NHL. Nested PCR was a good, time-saving and economical method for the accurate and early diagnosis of C. liquefaciens infections. Our presented case also showed that result of MALDI-TOF method was compatible with nested PCR method in identification of C. liquefaciens.en_US
dc.identifier.doi10.23736/S0393-3660.18.03746-4
dc.identifier.endpage166en_US
dc.identifier.issn0393-3660
dc.identifier.issn1827-1812
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85061057928
dc.identifier.scopusqualityQ4
dc.identifier.startpage163en_US
dc.identifier.urihttps://doi.org/10.23736/S0393-3660.18.03746-4
dc.identifier.urihttps://hdl.handle.net/11468/18914
dc.identifier.volume178en_US
dc.identifier.wosWOS:000461718600015
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherEdizioni Minerva Medicaen_US
dc.relation.ispartofGazzetta Medica Italiana Archivio Per Le Scienze Mediche
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCryptococcusen_US
dc.subjectPolymerase Chain Reactionen_US
dc.subjectMeningitisen_US
dc.titleCryptococcus liquefaciens meningitis in a patient with T cell non Hodgin lymphomaen_US
dc.titleCryptococcus liquefaciens meningitis in a patient with T cell non Hodgin lymphoma
dc.typeArticleen_US

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