Diagnostic contribution of focal cortical dysplasia MRI imaging findings and ADC values

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dc.contributor.authorAslan, Aydin
dc.contributor.authorDeniz, Muhammed Akif
dc.contributor.authorDeniz, Zelal Tas
dc.contributor.authorTurmak, Mehmet
dc.contributor.authorEkici, Faysal
dc.date.accessioned2024-04-24T17:14:56Z
dc.date.available2024-04-24T17:14:56Z
dc.date.issued2019
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackgroundFocal cortical dysplasia (FCD) is a condition that often interferes with the cranial mass. Knowledge of focal cortical dysplasia magnetic resonance imaging (MRI) characteristics is of utmost importance for diagnosis. This study aimed to determine the diagnostic contribution of cranial MRI and the apparent diffusion coefficient (ADC) in FCD.ResultsCranial MRI revealed subcortical hyperintensity (SCH) in 52 patients (82.5%), blurring of the gray-white matter (GWM) interface (blurring) in 52 patients (82.5%), cortical thickening (CT) in 48 patients (76%), cortical signal increase (CSI) in 41 patients (65%), and transmantle sign (TMS) in 29 patients (46%). All of the FCDs had a diffusion increase in diffusion-weighted images (DWIs). The mean ADC value at the lesion level was 1.087 x 10(-3) mm(2)/s (0.82/1.316 x 10(-3) mm(2)/s), which was significantly higher than the mean ADC value measured from the contralateral symmetric region (0.758 x 10(-3) mm(2)/s, 0.678/0.872 x 10(-3) mm(2)/s, p = 0.001).ConclusionResults of this study revealed that the most common MRI findings in FCD patients are SCH, blurring, and CT. These findings aid in an easier diagnosis in patients with suspected FCD. All of the lesions studied here in had a diffusion increase in DWI. The quantitative mean ADC values detected in the differential diagnosis of other lesions with a diffusion increase can be used as a reference. Therefore, in addition to the ADC values and electroencephalography (EEG) findings, the conventional MRI findings of FCD, which is resistant to medical treatment, can help to facilitate the diagnosis of FCD, which can be treated with surgery.en_US
dc.identifier.doi10.1186/s43055-019-0022-y
dc.identifier.issn2090-4762
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85071767163
dc.identifier.scopusqualityQ3
dc.identifier.urihttps://doi.org/10.1186/s43055-019-0022-y
dc.identifier.urihttps://hdl.handle.net/11468/18262
dc.identifier.volume50en_US
dc.identifier.wosWOS:000485002400006
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofEgyptian Journal of Radiology and Nuclear Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectFocal Cortical Dysplasiaen_US
dc.subjectMagnetic Resonance Imagingen_US
dc.subjectApparent Diffusion Coefficienten_US
dc.titleDiagnostic contribution of focal cortical dysplasia MRI imaging findings and ADC valuesen_US
dc.titleDiagnostic contribution of focal cortical dysplasia MRI imaging findings and ADC values
dc.typeArticleen_US

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