Comparison of the Effect of Periodontal Therapy and Diode Decontamination and Periodontal Therapy Alone on the Amount of TNF-? in Systemically Healthy Chronic Periodontitis Patients

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dc.contributor.authorDoğru A.G.
dc.contributor.authorToprak Ö.
dc.contributor.authorÜner D.D.
dc.contributor.authorİzol B.S.
dc.contributor.authorKaplan İ.
dc.contributor.authorDoğru M.
dc.contributor.authorİpek F.
dc.date.accessioned2024-04-24T18:46:15Z
dc.date.available2024-04-24T18:46:15Z
dc.date.issued2020
dc.departmentDicle Üniversitesien_US
dc.description.abstractOBJECTIVE: To evaluate the outcome of initial periodontal therapy and additional diode laser decontamination therapy on clinical parameters and the amount of tumor necrosis factor alpha (TNF?) in gingival crevicular fluid (GCF) in patients with chronic periodontitis. STUDY DESIGN: The study included 22 patients who were diagnosed with chronic periodontitis and who had at least 1 (?5 mm) periodontal pocket in the posterior region of each upper left hemiarcade. The study was designed as a splitmouth study involving mechanical therapy on the right side and nonsurgical periodontal therapy plus diode laser decontamination therapy on the left side. RESULTS: A statistically significant decrease was observed in clinical parameters at 3 months when compared to the values at baseline in both treatment areas. The change in clinical parameters at 3 months after therapy was not significantly different between the groups (p>0.05). The comparison of GCF TNF? levels at baseline and at 3 months in the 2 treatment areas identified significant changes in the TNF? levels in the hemiarcade treated with laser diode contamination therapy, whereas the changes in the hemiarcade treated with nonsurgical periodontal therapy were not significant (p>0.05). A betweengroup comparison revealed no statistically significant difference at 3 months posttherapy, while the difference at 1 month was found to be statistically significant. CONCLUSION: The study found that laser therapy in addition to nonsurgical periodontal therapy has a positive effect on the clinical parameters and proinflammatory TNF? levels in the early period but makes no contribution in the long term. © 2020 Science Printers and Publishers Inc.. All rights reserved.en_US
dc.identifier.endpage188en_US
dc.identifier.issn2578-742X
dc.identifier.issue6en_US
dc.identifier.scopus2-s2.0-85174356779
dc.identifier.scopusqualityQ4
dc.identifier.startpage180en_US
dc.identifier.urihttps://hdl.handle.net/11468/25124
dc.identifier.volume42en_US
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherScience Printers and Publishers Inc.en_US
dc.relation.ispartofAnalytical and Quantitative Cytopathology and Histopathology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectChronic Periodontitisen_US
dc.subjectDental Plaqueen_US
dc.subjectDental Scalingen_US
dc.subjectDental Surgeryen_US
dc.subjectDiode Laseren_US
dc.subjectGingival Crevicular Fluiden_US
dc.subjectLasersen_US
dc.subjectNonsurgical Periodontal Therapyen_US
dc.subjectPeriodontal Attachment Lossen_US
dc.subjectPeriodontal Diseasesen_US
dc.subjectPeriodontal Pocketen_US
dc.subjectPeriodontitisen_US
dc.subjectTnf-?en_US
dc.subjectTumor Necrosis Factor Alphaen_US
dc.titleComparison of the Effect of Periodontal Therapy and Diode Decontamination and Periodontal Therapy Alone on the Amount of TNF-? in Systemically Healthy Chronic Periodontitis Patientsen_US
dc.titleComparison of the Effect of Periodontal Therapy and Diode Decontamination and Periodontal Therapy Alone on the Amount of TNF-? in Systemically Healthy Chronic Periodontitis Patients
dc.typeArticleen_US

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