HISTOPATHOLOGIC EFFECTS OF GLASS IONOMER BONE CEMENTS APPLICATION TO MAXILLOFACIAL AREA: AN EXPERIMENTAL STUDY IN RABBITS

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dc.contributor.authorYorgancilar, Ediz
dc.contributor.authorFirat, Ugur
dc.contributor.authorGun, Ramazan
dc.contributor.authorBakir, Salih
dc.contributor.authorDasdag, Suleyman
dc.contributor.authorAkkus, Zeki
dc.contributor.authorGokalp, Osman
dc.date.accessioned2024-04-24T17:27:41Z
dc.date.available2024-04-24T17:27:41Z
dc.date.issued2012
dc.departmentDicle Üniversitesien_US
dc.description.abstractReconstruction of the maxillofacial bone defects and fractures poses a challenge to the surgeons. Various alternatives and materials have been described for these defects and fractures. Glass ionomer bone cements (GICs) have been used extensively in dentistry but recently they have also been utilized in otolaryngology. We hypothesized that GIC can be an alternative material for maxillofacial reconstruction. However, their biocompatibility is of primary importance because this material will be in direct contact with the tissue for a prolonged tune and might affect it. Therefore the aim of this study was to investigate the tissue responses to GIG in the maxillofacial area in rabbits. The study was carried out on 16 New Zealand White rabbits, which were divided into study (n: 8) and control (n: 8) groups. Experimental defects and fractures were created in the nasal bone, maxilla and zygoma in both the study and the control group. The experimental fractures and defects were reconstructed by GIG in the study group. However, the rabbits in the control group were left to natural healing process. The inflammatory reaction and fibrosis in the rabbits of both the study and the control group were compared by using descriptive histopathological analysis 180 days after application. The tissue reactions were graded. GIG showed a slight inflammatory and fibrous reaction in the rabbit of the study group. Nevertheless, statistical difference between the groups was not observed in terms of inflammatory reaction and fibrosis (P>0.05). The results of this study indicated that GIG is a well tolerated material in maxillofacial reconstruction.en_US
dc.description.sponsorshipDicle University; Research and Project Coordination Center; Department of Pathologyen_US
dc.description.sponsorshipThe authors are grateful to Dicle University, Research and Project Coordination Center and Department of Pathology for their valuable support.en_US
dc.identifier.doi10.5504/BBEQ.2011.0150
dc.identifier.endpage2780en_US
dc.identifier.issn1310-2818
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-84857557659
dc.identifier.scopusqualityQ3
dc.identifier.startpage2777en_US
dc.identifier.urihttps://doi.org/10.5504/BBEQ.2011.0150
dc.identifier.urihttps://hdl.handle.net/11468/20139
dc.identifier.volume26en_US
dc.identifier.wosWOS:000300542200015
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherDiagnosis Press Ltden_US
dc.relation.ispartofBiotechnology & Biotechnological Equipment
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBone Cementsen_US
dc.subjectGlass Ionomeren_US
dc.subjectMaxillofacialen_US
dc.subjectReconstructionen_US
dc.titleHISTOPATHOLOGIC EFFECTS OF GLASS IONOMER BONE CEMENTS APPLICATION TO MAXILLOFACIAL AREA: AN EXPERIMENTAL STUDY IN RABBITSen_US
dc.titleHISTOPATHOLOGIC EFFECTS OF GLASS IONOMER BONE CEMENTS APPLICATION TO MAXILLOFACIAL AREA: AN EXPERIMENTAL STUDY IN RABBITS
dc.typeArticleen_US

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