Urinary expression of acute kidney injury biomarkers in patients after RIRS: it is a prospective, controlled study
dc.contributor.author | Dede, Onur | |
dc.contributor.author | Dagguli, Mansur | |
dc.contributor.author | Utangac, Mazhar | |
dc.contributor.author | Yuksel, Hatice | |
dc.contributor.author | Bodakci, Mehmet Nuri | |
dc.contributor.author | Hatipoglu, Namik Kemal | |
dc.contributor.author | Sancaktutar, Ahmet Ali | |
dc.date.accessioned | 2024-04-24T17:40:13Z | |
dc.date.available | 2024-04-24T17:40:13Z | |
dc.date.issued | 2015 | |
dc.department | Dicle Üniversitesi | en_US |
dc.description.abstract | Objective: To evaluated the damage effects of retrograde intra-renal surgery (RIRS) on kidney tissue by measuring kidney injury molecule-1 (KIM-1), neutrophil gelatinase-associated lipocalin (NGAL), N-acetyl-beta-Dglucosaminidase (NAG), liver-type fatty acid binding protein (LFABP) expression. Material and methods: We enrolled thirty consecutive patients (Group 1) who underwent RIRS that presented with renal calculi size <2 cm. Forty-seven control patients (Group 2) with no signs or symptoms of urogenital disease were also enrolled for this study. Patients urine KIM-1, NGAL, NAG, and LFABP and creatinine levels were determined before the surgery, 2 hours after the surgery, and 24 hours after the surgery. Results: Demographic data were established and found to be similar between the two groups. Two hours after the surgery KIM-1/Cr and NGAL/Cr levels had increased significantly in urine compared to levels before the surgery (P:0.04, P:0.02 respectively) and decreased 24 hours after the surgery. The NAG/Cr and LFABP/Cr levels did not change significantly after the surgery. Conclusion: According to acute kidney injury (AKI) markers, this study is suggests that RIRS is a safe method, KIM-1/Cr and NGAL/Cr levels were increased first 2 hours but returned to initial levels within 24 hours after the surgery. | en_US |
dc.identifier.endpage | 8152 | en_US |
dc.identifier.issn | 1940-5901 | |
dc.identifier.issue | 5 | en_US |
dc.identifier.pmid | 26221383 | |
dc.identifier.startpage | 8147 | en_US |
dc.identifier.uri | https://hdl.handle.net/11468/21686 | |
dc.identifier.volume | 8 | en_US |
dc.identifier.wos | WOS:000359293200183 | |
dc.identifier.wosquality | Q4 | |
dc.indekslendigikaynak | Web of Science | |
dc.indekslendigikaynak | PubMed | |
dc.language.iso | en | en_US |
dc.publisher | E-Century Publishing Corp | en_US |
dc.relation.ispartof | International Journal of Clinical and Experimental Medicine | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Retrograde Intra-Renal Surgery | en_US |
dc.subject | Acute Kidney Injury | en_US |
dc.subject | Kidney Injury Molecule-1 | en_US |
dc.subject | Neutrophil Gelatinase-Associated Lipocalin | en_US |
dc.subject | N-Acetyl-Beta-D-Glucosaminidase | en_US |
dc.title | Urinary expression of acute kidney injury biomarkers in patients after RIRS: it is a prospective, controlled study | en_US |
dc.title | Urinary expression of acute kidney injury biomarkers in patients after RIRS: it is a prospective, controlled study | |
dc.type | Article | en_US |