Chemical profile, antioxidant properties and enzyme inhibitory effects of the root extracts of selected Potentilla species

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dc.authorid0000-0002-4090-7227en_US
dc.contributor.authorUysal, Şengül
dc.contributor.authorZengin, Gökhan
dc.contributor.authorMahomoodally, Fawzi M.
dc.contributor.authorYılmaz, Mustafa Abdullah
dc.contributor.authorAktümsek, Abdurrahman
dc.date.accessioned2022-03-02T07:00:39Z
dc.date.available2022-03-02T07:00:39Z
dc.date.issued2019en_US
dc.departmentDicle Üniversitesi, Bilim ve Teknoloji Uygulama ve Araştırma Merkezien_US
dc.description.abstractPlants from the genus Potentilla have been traditionally used for therapeutic purposes in Turkey. Methanol root extracts from four selected Potentilla species (P. anatolica, P. argentea, P. recta, and P. reptans) were probed for their chemical composition, antioxidant properties (DPPH, ABTS, FRAP, CUPRAC, phosphomolybdenum, and metal chelating activity), and enzyme (acetylcholinesterase (AChE), butyrylcholinesterase (BChE), α-amylase, α-glucosidase, and tyrosinase) inhibition effects. In addition, the total phenolic, flavonoid, saponin, and triterpenoid content of the extracts were determined. Ultra-high performance liquid chromatography (UHPLC)-electrospray ionization (ESI)-tandem mass spectrometry (MS/MS) analysis revealed that the main phenolic components in extracts were coumarin, hesperidin, p-coumaric acid, gallic acid, and rutin. P. recta and P. reptans showed the highest total phenolic, saponin, and triterpenoid content. The root extracts showed significant antioxidant properties and depicted significant inhibitory effects against AChE, BChE, α-amylase, α-glucosidase, and tyrosinase. In conclusion, root extracts of Potentilla may be considered as new natural antioxidants and key enzyme inhibitors that can be exploited as bioproducts for pharmaceutical industriesen_US
dc.identifier.citationUysal, Ş., Zengin, G., Mahomoodally, F. M., Yılmaz, M. A. ve Aktümsek, A. (2019). Chemical profile, antioxidant properties and enzyme inhibitory effects of the root extracts of selected Potentilla species. South African Journal of Botany, 120, 124-128.en_US
dc.identifier.doi10.1016/j.sajb.2018.01.014
dc.identifier.endpage128en_US
dc.identifier.issn0254-6299
dc.identifier.scopus2-s2.0-85041210648
dc.identifier.scopusqualityQ1
dc.identifier.startpage124en_US
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0254629917315442?via%3Dihub
dc.identifier.urihttps://hdl.handle.net/11468/9282
dc.identifier.volume120en_US
dc.identifier.wosWOS:000456314600014
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorYılmaz, Mustafa Abdullah
dc.language.isoenen_US
dc.publisherElsevier B.V.en_US
dc.relation.ispartofSouth African Journal of Botany
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBiaoctive agentsen_US
dc.subjectNatural productsen_US
dc.subjectPhenolicsen_US
dc.subjectPotentillaen_US
dc.subjectTurkeyen_US
dc.titleChemical profile, antioxidant properties and enzyme inhibitory effects of the root extracts of selected Potentilla speciesen_US
dc.titleChemical profile, antioxidant properties and enzyme inhibitory effects of the root extracts of selected Potentilla species
dc.typeArticleen_US

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