Effects of 50 Hz electric field on malondyaldehide and nitric oxide levels in spinal cord of rats at prenatal plus postnatal period

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dc.contributor.authorUzar, Ertugrul
dc.contributor.authorYilmaz, H. Ramazan
dc.contributor.authorYilmaz, Mustafa
dc.contributor.authorUz, Efkan
dc.contributor.authorYurekli, Vedat Ali
dc.contributor.authorDundar, Bumin
dc.contributor.authorKoyuncuoglu, Hasan Rifat
dc.date.accessioned2024-04-24T17:21:07Z
dc.date.available2024-04-24T17:21:07Z
dc.date.issued2011
dc.departmentDicle Üniversitesien_US
dc.description.abstractAim: The effect of 50 Hz electric field (EF) on developing neural tissues is not known. We aimed to determine whether there would be any oxidative stress effect of 50 Hz EF on developing spinal cord tissues of pup rats by evaluating malondialdehyde (MDA), nitric oxide (NO) levels, and antioxidant enzyme activities such as superoxide dismutase (SOD) and catalase (CAT) measurement. Materials and methods: In the prenatal+postnatal group, the pregnant rat was exposed to continuous EF at 50 Hz 10 kV/s until delivery. Then the female pups of this group (n = 7) were exposed to EF at the same doses and for the same duration until puberty. In the postnatal group, the pregnant rat was unexposed to EF during pregnancy, but the female pups from this group (n = 7) began to be exposed to EF at delivery, and continued to be exposed to EF at 50 Hz EF 10 kV/m for 24 h until puberty. Results: In the prenatal+postnatal group, the MDA and NO levels in the spinal cord tissue of pup rats were significantly higher when compared to the control group. However, in the postnatal group, the MDA and NO levels in the spinal cord tissue of pup rats were not significantly different when compared to the control group. Conclusion: A 50 Hz electric field may cause oxidative stress in the spinal cord of rats in the prenatal+postnatal period.en_US
dc.identifier.doi10.3906/sag-0910-383
dc.identifier.endpage72en_US
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.issue1en_US
dc.identifier.startpage65en_US
dc.identifier.trdizinid111823
dc.identifier.urihttps://doi.org/10.3906/sag-0910-383
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/111823
dc.identifier.urihttps://hdl.handle.net/11468/19373
dc.identifier.volume41en_US
dc.identifier.wosWOS:000288413100009
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakTR-Dizin
dc.language.isoenen_US
dc.publisherTubitak Scientific & Technological Research Council Turkeyen_US
dc.relation.ispartofTurkish Journal of Medical Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectElectric Fielden_US
dc.subjectOxidative Stressen_US
dc.subjectNitric Oxideen_US
dc.subjectMalondialdehydeen_US
dc.subjectSpinal Corden_US
dc.titleEffects of 50 Hz electric field on malondyaldehide and nitric oxide levels in spinal cord of rats at prenatal plus postnatal perioden_US
dc.titleEffects of 50 Hz electric field on malondyaldehide and nitric oxide levels in spinal cord of rats at prenatal plus postnatal period
dc.typeArticleen_US

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