Ectopic bone formation in thyroid gland: report of sixteen cases and comprehensive literature review

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dc.contributor.authorSogutcu, N.
dc.contributor.authorAkbulut, S.
dc.contributor.authorSari, A.
dc.contributor.authorYavuz, R.
dc.contributor.authorYagmur, Y.
dc.contributor.authorColak, C.
dc.date.accessioned2024-04-24T17:48:11Z
dc.date.available2024-04-24T17:48:11Z
dc.date.issued2023
dc.departmentDicle Üniversitesien_US
dc.description.abstract- OBJECTIVE: This study aimed to analyze the outcomes of patients with ectopic bone formation (EBF) diagnosed in thyroidecto-my specimen.PATIENTS AND METHODS: We retrospec-tively analyzed the data of 16 patients who un-derwent thyroidectomy between February 2009 and June 2018 and whose pathology examina-tion diagnosed EBF. RESULTS: Fourteen patients underwent bilat-eral total thyroidectomy (BTT), one patient re-quired BTT with central lymph node dissection, and one patient was subjected to BTT with func-tional lymph node dissection. On histopatholog-ical examination, left lobe EBF was diagnosed in four patients; left lobe EBF with bilateral pap-illary thyroid carcinoma (PTC) in two; left lobe EBF with left lobe PTC in one; left lobe EBF with left follicular adenoma in one; left lobe EBF with right lobe papillary thyroid microcarcinoma in one; bilateral EBF in one; right lobe EBF with ex-tramedullary hematopoiesis in one; right lobe EBF in three; right lobe EBF with right lobe med-ullary thyroid carcinoma in one, and right lobe EBF with bilateral lymphocytic thyroiditis in one. One of the five patients who underwent bone marrow biopsy was diagnosed with myelopro-liferative dysplasia, and another with polycythe-mia vera. Three patients were treated medically for anemia because no other pathological find-ings could be observed.CONCLUSIONS: There is a lack of literature data about the clinical significance of EBF in the thyroid gland in cases with no concomitant he-matological diseases. People who have been di-agnosed with EBF in the thyroid gland should be checked for hematological diseases.en_US
dc.identifier.endpage998en_US
dc.identifier.issn1128-3602
dc.identifier.issue3en_US
dc.identifier.pmid36808344
dc.identifier.startpage988en_US
dc.identifier.urihttps://hdl.handle.net/11468/22917
dc.identifier.volume27en_US
dc.identifier.wosWOS:000951507500020
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherVerduci Publisheren_US
dc.relation.ispartofEuropean Review For Medical and Pharmacological Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectKey Thyroiden_US
dc.subjectMultinodular Goiteren_US
dc.subjectEctopic Bone Formationen_US
dc.subjectOsseous Metaplasiaen_US
dc.titleEctopic bone formation in thyroid gland: report of sixteen cases and comprehensive literature reviewen_US
dc.titleEctopic bone formation in thyroid gland: report of sixteen cases and comprehensive literature review
dc.typeReview Articleen_US

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