The Effect of Vitamin D Levels in Multisystem Inflammatory Syndrome in Children

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dc.contributor.authorKan, Ahmet
dc.contributor.authorTure, Mehmet
dc.contributor.authorAkin, Alper
dc.contributor.authorYilmaz, Kamil
dc.contributor.authorSurucu, Mehmet
dc.contributor.authorUnal, Edip
dc.contributor.authorSen, Velat
dc.date.accessioned2024-04-24T16:24:10Z
dc.date.available2024-04-24T16:24:10Z
dc.date.issued2022
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjective Multiple factors being overweight, asthmatic, or being of Asian or black ethnic origins have been reported vis-a-vis the multisystem inflammatory syndrome in children (MIS-C). There is an association between these conditions and vitamin D deficiency, which explains why MIS-C is more common in these patients. In the present study, we attempted to retrospective evaluate the 25-hydroxy vitamin D levels of patients with MIS-C, its association with acute phase reactants, its treatment, and clinical status. Methods Patients aged between 1.5 months to 18 years with MIS-C were included in the study. All of the laboratory parameters, treatment, and response to the treatment were evaluated retrospectively. Two groups were formed. Patients had 25-hydroxycholecalciferol D vitamin < 20 ng/mL in group 1 and >= 20 ng/mL in group 2. Results A total of 52 patients were included in the study. There was no statistical difference between groups in terms of acceptance of the intensive care unit treatment (p = 0.29) and response to the first-line treatment (p = 0.56). A lower median lymphocyte count (p = 0.01) and a higher median C-reactive protein (p = 0.04) and procalcitonin (p = 0.01) with N-terminal pro-B-type natriuretic peptide (p = 0.025) values were found in group 1. Conclusion Vitamin D deficiency was associated with an increased inflammatory response in children with MIS-C. More studies are required to determine the potential impact of vitamin D deficiency on the clinical outcome of MIS-C.en_US
dc.identifier.doi10.1055/s-0042-1749372
dc.identifier.endpage199en_US
dc.identifier.issn1305-7707
dc.identifier.issn1305-7693
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-85134485008
dc.identifier.scopusqualityQ4
dc.identifier.startpage194en_US
dc.identifier.urihttps://doi.org/10.1055/s-0042-1749372
dc.identifier.urihttps://hdl.handle.net/11468/16544
dc.identifier.volume17en_US
dc.identifier.wosWOS:000822880400005
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherGeorg Thieme Verlag Kgen_US
dc.relation.ispartofJournal of Pediatric Infectious Diseases
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMultisystem Inflammatory Syndromeen_US
dc.subjectVitamin Den_US
dc.subjectInflammation Parametersen_US
dc.titleThe Effect of Vitamin D Levels in Multisystem Inflammatory Syndrome in Childrenen_US
dc.titleThe Effect of Vitamin D Levels in Multisystem Inflammatory Syndrome in Children
dc.typeArticleen_US

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