Thyroid Tuberculosis in Southeastern Turkey: Is This the Resurgence of a Stubborn Disease?

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dc.contributor.authorAkbulut, Sami
dc.contributor.authorSogutcu, Nilgun
dc.contributor.authorArikanoglu, Zulfu
dc.contributor.authorBakir, Sule
dc.contributor.authorUlku, Abdullah
dc.contributor.authorYagmur, Yusuf
dc.date.accessioned2024-04-24T15:59:57Z
dc.date.available2024-04-24T15:59:57Z
dc.date.issued2011
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground While tuberculosis (TB) has been found in many parts of the body, involvement of the thyroid gland is rare. In this study we describe the clinicopathological characteristics of seven patients with primary thyroid tuberculosis (TTB). Methods This report is a retrospective case study of seven patients with thyroid tuberculosis who were treated surgically in our clinic between 2004 and 2010. Data collected from the cases included age, sex, clinical presentation, concurrent medical illness, initial diagnosis, and history of pulmonary tuberculosis. Testing used to establish the diagnosis of TTB included thyroid function tests, histopathological examination, a tuberculin skin test, and FNAC (fine needle aspiration cytology). Surgical procedures, antitubercular therapy, and follow-up data were also analyzed. Results All seven cases were females between the age of 30 and 60 years (mean = 44.1 +/- 9.5 years). Four cases had neck swelling and three had additional complaints of dysphagia and dyspnea. While total thyroidectomy was performed in six patients with multinodular goiter, a lobectomy was performed in one patient in whom a solitary thyroid nodule was detected. Histopathologic changes consistent with thyroid tuberculosis were detected in all patients. Thoracic X-ray, erythrocyte sedimentation rate (ESR) test, and tuberculin skin test (PPD) were performed and all patients were screened for other possible foci of infection. In conclusion, all seven cases were diagnosed with primary tuberculosis. While the lobectomy patient was administered a 6-month antitubercular treatment, the total-thyroidectomy patients did not receive any medical treatment postoperatively. During the postoperative followup period, which lasted between 6 and 53 months (mean = 37.3 +/- 18.6 months), none of the patients had a recurrence of disease. Conclusion Tuberculosis should be considered in the list of differential diagnoses for thyroid abscesses and nodular lesions in people living in geographic regions with a high tuberculosis prevalence.en_US
dc.identifier.doi10.1007/s00268-011-1118-3
dc.identifier.endpage1852en_US
dc.identifier.issn0364-2313
dc.identifier.issn1432-2323
dc.identifier.issue8en_US
dc.identifier.pmid21523497
dc.identifier.startpage1847en_US
dc.identifier.urihttps://doi.org/10.1007/s00268-011-1118-3
dc.identifier.urihttps://hdl.handle.net/11468/14323
dc.identifier.volume35en_US
dc.identifier.wosWOS:000293705300023
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofWorld Journal of Surgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject[No Keyword]en_US
dc.titleThyroid Tuberculosis in Southeastern Turkey: Is This the Resurgence of a Stubborn Disease?en_US
dc.titleThyroid Tuberculosis in Southeastern Turkey: Is This the Resurgence of a Stubborn Disease?
dc.typeArticleen_US

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