Evaluation of prognosis by complete blood parameters in patients with acute pulmonary embolism

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dc.contributor.authorIcer, Mustafa
dc.contributor.authorTekin, Veysi
dc.date.accessioned2025-02-22T14:08:44Z
dc.date.available2025-02-22T14:08:44Z
dc.date.issued2025
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground: Acute pulmonary embolism is associated with high death and morbidity. During a pulmonary embolism, neutrophils infiltrate the right ventricular wall, inflammatory mediators are released, and necrosis develops. This study aimed to compare the effectiveness of whole blood parameters mean platelet volume (MPV), mean platelet volume to platelet ratio (MPVPR), neutrophils (NEU), neutrophil-tolymphocyte platelet ratio (NLPR), neutrophil to lymphocyte ratio (NLR), neutrophil to platelet ratio (NPR), platelets (PLT), platelet mass index (PMI), and systemic immuneinflammatory index (SII) in predicting mortality in patients with acute pulmonary embolism. Methods: We retrospectively analyzed 112 patients diagnosed with acute pulmonary embolism at Dicle University Hospital's emergency department between January 2016 and December 2022. Receiver operating characteristic (ROC) curve analysis was used to examine the diagnostic decision properties of the variables used in mortality prediction. Results: 103 (91.96%) of the patients survived and 9 (8.04%) died. As a result, the best parameters for predicting mortality outcomes were NLPR (area under the curve (AUC): 0.887, sensitivity: 88.89%, specificity: 84.47%, positive predictive value (PPV): 33.33%, negative predictive value (NPV): 98.86%), NPR (AUC: 0.828, sensitivity: 77.78%, specificity: 91.26%, PPV: 43.75%, NPV: 97.92%), NLR (AUC: 0.803, sensitivity: 88.89%, specificity: 60.19%, PPV: 16.33%, NPV: 98.41%) respectively. Conclusions: This study found that NLPR, NPR and NLR were the most accurate complete blood parameters for predicting mortality in acute pulmonary embolism patients admitted to the emergency department.en_US
dc.identifier.doi10.22514/sv.2025.006
dc.identifier.endpage51en_US
dc.identifier.issn1334-5605
dc.identifier.issn1845-206X
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85215765267en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage45en_US
dc.identifier.urihttps://doi.org/10.22514/sv.2025.006
dc.identifier.urihttps://hdl.handle.net/11468/29606
dc.identifier.volume21en_US
dc.identifier.wosWOS:001393247100007
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherMre Pressen_US
dc.relation.ispartofSigna Vitaeen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKA_WOS_20250222
dc.subjectAcute pulmonary embolismen_US
dc.subjectNeutrophil-to-lymphocyte platelet ratio (NLPR)en_US
dc.subjectNeu- trophil to lymphocyte ratio (NLR)en_US
dc.subjectNeutrophil to platelet ratio (NPR)en_US
dc.subjectMortaliteen_US
dc.titleEvaluation of prognosis by complete blood parameters in patients with acute pulmonary embolismen_US
dc.typeArticleen_US

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