The Evaluation of Nasal Cultures in Patients with Hematological Malignancies During Febrile Neutropenic Episodes

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dc.contributor.authorUlug, Mehmet
dc.contributor.authorAyaz, Celal
dc.contributor.authorCelen, Mustafa Kemal
dc.date.accessioned2024-04-24T17:24:24Z
dc.date.available2024-04-24T17:24:24Z
dc.date.issued2012
dc.departmentDicle Üniversitesien_US
dc.description.abstractAim: Febrile neutropenia is a common complication in patients receiving cancer treatment. According to the results of several investigations, bacterial infections are the most common causes of morbidity and mortality in these patients. In this study, we aimed to determine the prevalence of nasal carriage of S. aureus in patients with febrile neutropenia, to assess the frequency of methicillin resistant S. aureus, and to compare the blood and nasal cultures in these patients. Methods: Nasal and blood cultures were performed in 51 patients with hematological malignancies during febrile neutropenic episodes. Antimicrobial susceptibilities of all S. aureus and Gram-negative strains were evaluated by disc diffusion method according to the National Committee for Clinical Laboratory Standards (NCCLS) for oxacillin and several other antibiotics. Results: In this study, blood and nasal cultures obtained between March 2006 and September 2006 were evaluated retrospectively. The overall nasal S. aureus carriage rate was 23.5%. On the other hand, of all blood cultures performed in 51 patients, nine (17.5%) were positive and the bacteria were not isolated in 87.5% of patients. The overall compliance rate of strains isolated from both blood and nasal cultures was 17.5%, while it was 11.7% when considering the status of strains resistant to antibiotics studied. Conclusion: It is concluded that, the surveillance cultures made occasionally in patients with febrile neutropenia may give an idea to the physicians in cases in which the causative pathogen cannot be determined.en_US
dc.identifier.doi10.4274/Haseki.754
dc.identifier.endpage141en_US
dc.identifier.issn1302-0072
dc.identifier.issn2147-2688
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-84871568263
dc.identifier.scopusqualityQ3
dc.identifier.startpage136en_US
dc.identifier.urihttps://doi.org/10.4274/Haseki.754
dc.identifier.urihttps://hdl.handle.net/11468/19652
dc.identifier.volume50en_US
dc.identifier.wosWOS:000216734400006
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isotren_US
dc.publisherGalenos Yayinciliken_US
dc.relation.ispartofHaseki Tip Bulteni-Medical Bulletin of Haseki
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectFebrile Neutropeniaen_US
dc.subjectNasal Carriageen_US
dc.subjectStaphylococcus Aureusen_US
dc.subjectSurveillance Cultureen_US
dc.titleThe Evaluation of Nasal Cultures in Patients with Hematological Malignancies During Febrile Neutropenic Episodesen_US
dc.titleThe Evaluation of Nasal Cultures in Patients with Hematological Malignancies During Febrile Neutropenic Episodes
dc.typeArticleen_US

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