The importance of fusidic acid in the treatment of chronic osteomyelitis

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dc.contributor.authorUlu? M.
dc.contributor.authorAyaz C.
dc.contributor.authorÇelen M.K.
dc.date.accessioned2024-04-24T17:59:00Z
dc.date.available2024-04-24T17:59:00Z
dc.date.issued2009
dc.departmentDicle Üniversitesien_US
dc.description.abstractIn recent years, high resistance to antibiotics used for staphylococci infections causes problems in the treatment. The aim of this study was to investigate the susceptibilities of staphylococcus strains which were isolated in bone tissue and sinus-tract specimens of chronic osteomyelitis (COM) that were seen in our hospital against fusidic acid, vancomycin and teicoplanin that were also recommended as treatment of staphylococci infections. Disk diffusion method was used for in vitro susceptibility testing. In this study, 41 Staphylococcus aureus and 12 coagulase-negative staphylococci strains isolated from bone tissue and sinus-tract were investigated. The rates of resistance to fusidic acid were 4.3% in methicillin-sensitive S. aureus, 16.7% in methicillin-resistant S. aureus, 0% in methicillin-sensitive coagulase-negative staphylococci and 36% in methicillin-resistant coagulase-negative staphylococci. There were no resistance to vancomycin and teicoplanin in none of the strains. The high sensitivity of staphylococci strains to fusidic acid indicates that fusidic acid is a good alternative for the treatment of COM caused by staphylococci.en_US
dc.identifier.endpage226en_US
dc.identifier.issn1306-8814
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-77953422181en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage222en_US
dc.identifier.urihttps://hdl.handle.net/11468/24189
dc.identifier.volume3en_US
dc.indekslendigikaynakScopus
dc.language.isotren_US
dc.relation.ispartofAnatolian Journal of Clinical Investigationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleThe importance of fusidic acid in the treatment of chronic osteomyelitisen_US
dc.title.alternativeStafi?lokokkal kroni?k osteomi?yeli?t tedavi?si?nde fusi?di?k asi?di?n yeri?en_US
dc.typeArticleen_US

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