Use of Flame Atomic Absorption Spectrometry in Diagnosis of Cancerous and Non-Cancerous Breast Tissues: Comparison of Metal Concentrations

Basit Öğe Kaydı
dc.contributor.authorKaya, Gokce
dc.contributor.authorAkdeniz, Ismail
dc.contributor.authorOzcan, Cemile
dc.contributor.authorKilinc, Ersin
dc.contributor.authorYaman, Mehmet
dc.date.accessioned2024-04-24T17:40:00Z
dc.date.available2024-04-24T17:40:00Z
dc.date.issued2010
dc.departmentDicle Üniversitesien_US
dc.description.abstractMetals play important roles for cellular functions and also for generating oxidative DNA damages. Furthermore, they are considered to act not only as carcinogens but also as co-carcinogens which activate carcinogenic chemicals. The question of whether trace metal concentrations in tissues increase or decrease in cancerous patients has not been answered with certainty, since the data in this area are both rare and include contrary results. This confusion can be attributed to differences in digestion methods of tissues and reliability of analysis techniques. In this study, concentrations of trace metals including Cd, Ni, Cu, Zn, Fe, Mg, and Ca in both cancerous and non-cancerous breast tissues were determined by flame atomic absorption spectrometry. The tissue samples were digested by using microwave energy. The average concentrations of Cu, Zn, Fe, Mg, and Ca were 0.7, 13, 22, 129 and 260 mu g/g, respectively) in cancerous women's breast tissues found to be significantly higher (p<0.05) than those in non-cancerous women's breast tissues (0.4, 7, 12, 55, and 165 mu g/g, respectively), for the paired samples. Thus, the concentration levels of these metals can be considered for diagnosis of cancerous and non-cancerous breast tissues.en_US
dc.identifier.endpage110en_US
dc.identifier.issn0195-5373
dc.identifier.issn2708-521X
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-77954547625
dc.identifier.scopusqualityQ2
dc.identifier.startpage102en_US
dc.identifier.urihttps://hdl.handle.net/11468/21521
dc.identifier.volume31en_US
dc.identifier.wosWOS:000279041900006
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherAtomic Spectroscopy Press Ltden_US
dc.relation.ispartofAtomic Spectroscopy
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject[No Keyword]en_US
dc.titleUse of Flame Atomic Absorption Spectrometry in Diagnosis of Cancerous and Non-Cancerous Breast Tissues: Comparison of Metal Concentrationsen_US
dc.titleUse of Flame Atomic Absorption Spectrometry in Diagnosis of Cancerous and Non-Cancerous Breast Tissues: Comparison of Metal Concentrations
dc.typeArticleen_US

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