Quality of life and related variables in patients with ankylosing spondylitis

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dc.contributor.authorBodur, Hatice
dc.contributor.authorAtaman, Sebnem
dc.contributor.authorRezvani, Aylin
dc.contributor.authorBugdayci, Derya Soy
dc.contributor.authorCevik, Remzi
dc.contributor.authorBirtane, Murat
dc.contributor.authorAkinci, Aysen
dc.date.accessioned2024-04-24T16:02:19Z
dc.date.available2024-04-24T16:02:19Z
dc.date.issued2011
dc.departmentDicle Üniversitesien_US
dc.description.abstractTo evaluate quality of life (QoL) and related variables in patients with ankylosing spondylitis (AS), a chronic inflammatory disease of the spine. Nine-hundred and sixty-two patients with AS from the Turkish League Against Rheumatism AS Registry, who fulfilled the modified New York criteria, were enrolled. The patients were evaluated using the Assessment of SpondyloArthritis International Society core outcome domains including Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), fatigue (BASDAI-question 1), pain (last week/spine/due to AS), Bath Ankylosing Spondylitis Functional Index (BASFI), Bath Ankylosing Spondylitis Metrology Index (BASMI), Bath Ankylosing Spondylitis Radiology Index (BASRI), Maastricht Ankylosing Spondylitis Enthesitis Score (MASES) and two QoL questionnaires (the disease-specific ASQoL and generic the Short Form-36 [SF-36]). The mean ASQoL score was 7.1 +/- A 5.7. SF-36 subscales of general health, physical role and bodily pain had the poorest scores. ASQoL was strongly correlated with disease duration, BASDAI, fatigue, BASFI, BASMI, BASRI, MASES, pain and SF-36 subscales (P < 0.001). SF-36 subscales were also strongly correlated with BASDAI and BASFI. Advanced educational status and regular exercise habits positively affected QoL, while smoking negatively affected QoL. In patients with AS, the most significant variables associated with QoL were BASDAI, BASFI, fatigue and pain. ASQoL was noted to be a short, rapid and simple patient-reported outcome (PRO) instrument and strongly correlated with SF-36 subscales.en_US
dc.description.sponsorshipWyeth/Pfizer Companyen_US
dc.description.sponsorshipThe authors express their gratitude to all members of the TRASD AS Study group for their cooperation and to Wyeth/Pfizer Company for the registery sponsorship.en_US
dc.identifier.doi10.1007/s11136-010-9771-9
dc.identifier.endpage549en_US
dc.identifier.issn0962-9343
dc.identifier.issn1573-2649
dc.identifier.issue4en_US
dc.identifier.pmid20978859
dc.identifier.startpage543en_US
dc.identifier.urihttps://doi.org/10.1007/s11136-010-9771-9
dc.identifier.urihttps://hdl.handle.net/11468/14741
dc.identifier.volume20en_US
dc.identifier.wosWOS:000289481100010
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofQuality of Life Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAnkylosing Spondylitisen_US
dc.subjectQuality Of Lifeen_US
dc.titleQuality of life and related variables in patients with ankylosing spondylitisen_US
dc.titleQuality of life and related variables in patients with ankylosing spondylitis
dc.typeArticleen_US

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