Comparative phytochemical and bioactivity studies on two related Scorzonera L. species: A chemotaxonomic contribution

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dc.authorid0000-0002-8325-8116en_US
dc.authorid0000-0002-1228-8932en_US
dc.authorid0000-0003-4163-9962en_US
dc.contributor.authorŞahin, Hasan
dc.contributor.authorDemir, Serhat
dc.contributor.authorBoğa, Mehmet
dc.contributor.authorSarı, Aynur
dc.contributor.authorMakbul, Serdar
dc.contributor.authorGültepe, Mutlu
dc.date.accessioned2024-02-23T11:46:57Z
dc.date.available2024-02-23T11:46:57Z
dc.date.issued2023en_US
dc.departmentDicle Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bililmleri Bölümüen_US
dc.description.abstractScorzonera L. (Asteraceae) is considered a taxonomically difficult genus with its more than 160 species. Scorzonera bella (SB) and S. veratrifolia (SV) species have been treated as synonyms since 1975. Recent botanical studies suggested the separation of the two taxa based on phenetic dissimilarities. Isolation, LC-MS/MS (including 53 phytochemicals as standard), and GC-MS (followed by library search) analyzes were conducted on the aerial parts of the plants to compare their phytochemical compositions and contribute to the classification of the two taxa. While flavonoid profile of SB was dominated by flavones, the majority of SV consisted of flavonols, among the analyzed standards. Nicotiflorin, the most abundant compound of SV, was the most notable difference which was not determined in SB. Kaempferol glycosides might be chemotaxonomic markers for the classification at subgenus levels. Caffeoylquinic acid esters were in common and similar amounts according to profiling and isolation results. Phytochemical compositions of nonpolar fractions of the plants differed significantly in phthalic acid esters, ursane, and hopane type triterpenoids which were only determined in SV. Phytochemical findings supported the separation of the two taxa. Antioxidant, anti-diabetic, anti-Alzheimer, and anti-hyperpigmentation potentials of the plants were evaluated in-vitro.en_US
dc.description.sponsorshipDUBAP (Dicle University Scientific Research Projects Coordinator)en_US
dc.identifier.citationŞahin, A., Demir, S., Bğa, M., Sarı, A., Makbul, S. ve Gültepe, M. (2023). Comparative phytochemical and bioactivity studies on two related Scorzonera L. species: A chemotaxonomic contribution. Biochemical Systematics and Ecology, 111, 104743.en_US
dc.identifier.doi10.1016/j.bse.2023.104743
dc.identifier.endpage8en_US
dc.identifier.issn0305-1978
dc.identifier.issn1873-2925
dc.identifier.scopus2-s2.0-85174564276
dc.identifier.scopusqualityQ2
dc.identifier.startpage1en_US
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0305197823001606?via%3Dihub
dc.identifier.urihttps://hdl.handle.net/11468/13376
dc.identifier.volume111en_US
dc.identifier.wosWOS:001100057300001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorŞahin, Hasan
dc.institutionauthorDemir, Serhat
dc.institutionauthorBoğa, Mehmet
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofBiochemical Systematics and Ecology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.relation.tubitak109T972
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectScorzonera bella & Scorzonera veratrifoliaen_US
dc.subjectFlavonoidsen_US
dc.subjectTerpenoidsen_US
dc.subjectPhthalatesen_US
dc.subjectChemotaxonomyen_US
dc.titleComparative phytochemical and bioactivity studies on two related Scorzonera L. species: A chemotaxonomic contributionen_US
dc.titleComparative phytochemical and bioactivity studies on two related Scorzonera L. species: A chemotaxonomic contribution
dc.typeArticleen_US

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