Indications and results of surgery in patients with Crohn's disease with onset under 10 years of age

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dc.contributor.authorDokucu, AI
dc.contributor.authorSarnacki, S
dc.contributor.authorMichel, JL
dc.contributor.authorJan, D
dc.contributor.authorGoulet, O
dc.contributor.authorRicour, C
dc.contributor.authorNihoul-Fekéte, C
dc.date.accessioned2024-04-24T16:24:10Z
dc.date.available2024-04-24T16:24:10Z
dc.date.issued2002
dc.departmentDicle Üniversitesien_US
dc.description.abstractIn order to examine the presentation and course of Crohn's disease (CD) with an onset of CD before the age of 10 and to assess indications and effects of surgery, a retrospective study was performed in 18 children. One hundred and twenty-two children with CD have been followed over the last 22 years in our institution. Thirty of them had the first onset of disease before 10 years of age. Eighteen out of these 30 underwent intestinal resection (IR), The mean age at the onset of CD was 6.4 years and the average duration of follow-up was 11.1 years. Most common symptoms were abdominal pain (72%), diarrhoea (72%), and growth retardation (50%). Colon and ileon were the most frequently involved areas. Most of the children (94.5%) received extensive medical and or nutritional treatment before surgery. We performed 26 IRs and 14 other operations in 18 patients. Indications for IR were chronic intestinal obstruction (13 cases) and chronic intestinal disability (13 cases). Improvements in the general clinical state were obtained in 17 cases out of 18. IR is beneficial for chronically ill children with ineffective medical therapy. A disease-free interval after surgery may provide an important time for improved growth and pubertal development and a return to nearly normal life for a long time.en_US
dc.identifier.doi10.1055/s-2002-32725
dc.identifier.endpage185en_US
dc.identifier.issn0939-7248
dc.identifier.issue3en_US
dc.identifier.pmid12101500
dc.identifier.startpage180en_US
dc.identifier.urihttps://doi.org/10.1055/s-2002-32725
dc.identifier.urihttps://hdl.handle.net/11468/16547
dc.identifier.volume12en_US
dc.identifier.wosWOS:000176745100007
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherGeorg Thieme Verlag Kgen_US
dc.relation.ispartofEuropean Journal of Pediatric Surgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCrohn's Disease In Childrenen_US
dc.subjectIntestinal Resectionen_US
dc.subjectInflammatory Diseaseen_US
dc.titleIndications and results of surgery in patients with Crohn's disease with onset under 10 years of ageen_US
dc.titleIndications and results of surgery in patients with Crohn's disease with onset under 10 years of age
dc.typeArticleen_US

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