Chemical compositions by LC-MS/MS and GC-MS and biological activities of Chenopodium album subsp. album var. microphyllum

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dc.contributor.authorYilmaz, Pelin Koseoglu
dc.contributor.authorErtas, Abdulselam
dc.contributor.authorAkdeniz, Mehmet
dc.contributor.authorAvci, Mine Kocyigit
dc.contributor.authorKolak, Ufuk
dc.date.accessioned2024-04-24T16:14:56Z
dc.date.available2024-04-24T16:14:56Z
dc.date.issued2019
dc.departmentDicle Üniversitesien_US
dc.description.abstractChenopodium species have been used in folk medicine and as vegetable for years. In the present study, the total phenolic and flavonoid contents, biological activities, phenolic constituents and fatty acid profile of Chenopodium album subsp. album var. microphyllum (Boen.) Aellen were determined for the first time. The antioxidant effects were investigated by 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging and cupric ion reducing antioxidant capacity assays (CUPRAC). The Ellman method was applied for the determination of the cholinesterase inhibition activity. The phenolic constituents of the methanol extract and the fatty acid profile of the n-hexane extract were evaluated by LC-MS/MS and GC-MS, respectively. Acetone and methanol extracts showed similar DPPH free radical scavenging activities (0.68 +/- 0.07 and 0.68 +/- 0.05 mmol Trolox/g extract, respectively), whereas the cupric ion reducing capacity of the acetone extract was the highest (0.41 +/- 0.05 mmol Trolox/g extract). Acetone and methanol extracts had moderate butyrylcholinesterase inhibitory activities as 65.29 +/- 1.56% and 52.64 +/- 2.78%, respectively, whereas non of the extracts possessed anti-acetylcholinesterase effect. The methanol extract was found to contain significant amounts of hesperidin (9769.13 +/- 158.26 mu g/g extract) and rutin (2935.19 +/- 39.92 mu g/g extract). The major fatty acid constituents of the n-hexane extract were identified as myristic acid (18.26%) and cis-10-pentadecanoic acid (15.39%).en_US
dc.identifier.doi10.1016/j.indcrop.2019.111755
dc.identifier.issn0926-6690
dc.identifier.issn1872-633X
dc.identifier.scopus2-s2.0-85072032326
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1016/j.indcrop.2019.111755
dc.identifier.urihttps://hdl.handle.net/11468/15536
dc.identifier.volume141en_US
dc.identifier.wosWOS:000496611800012
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofIndustrial Crops and Products
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAnticholinesteraseen_US
dc.subjectAntioxidanten_US
dc.subjectChenopodium Albumen_US
dc.subjectFatty Aciden_US
dc.subjectPhenolicen_US
dc.titleChemical compositions by LC-MS/MS and GC-MS and biological activities of Chenopodium album subsp. album var. microphyllumen_US
dc.titleChemical compositions by LC-MS/MS and GC-MS and biological activities of Chenopodium album subsp. album var. microphyllum
dc.typeArticleen_US

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