Effects of Adnexal Torsion on the Fallopian Tube in Rats A Histologic and Immunohistochemical Study

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dc.contributor.authorTung, Senem Yaman
dc.contributor.authorAgacayak, Elif
dc.contributor.authorYaman, Neval S.
dc.contributor.authorDeveci, Engin
dc.contributor.authorKalkanli, Sevgi
dc.contributor.authorOzler, Ali
dc.date.accessioned2024-04-24T17:44:21Z
dc.date.available2024-04-24T17:44:21Z
dc.date.issued2014
dc.departmentDicle Üniversitesien_US
dc.description.abstractOBJECTIVE: To investigate histopathological and immunohistochemical changes in the Fallopian tube structure following ovarian torsion. STUDY DESIGN: Thirty fertile, female, adult Wistar albino rats, weighing 200-220 g, were randomly divided into 3 equal groups (n=10): sham, torsion, and detorsion. In the torsion and detorsion groups, bilateral adnexal torsion (3-hour ischemia) was carried out. Bilateral adnexal detorsion (3-hour reperfusion) was performed in the detorsion group. Fallopian tube sections were stained hematoxylin and eosin, periodic acid Schiff, Mallory-Azan and immunohistochernically-stained desmin, a smooth actin, and CD68 antibodies. RESULTS: In the sections of the ischemic group, degeneration of epithelium, loss of cilia, dilation of blood vessels, and hemorrhages were observed. Image analysis of the studied Fallopian section revealed a significant decrease in density of desmin in the torsion group. Moreover, strong positive cytoplasmic CD68 expression was observed in the torsion group. CONCLUSION: The use of effective antiinflammatory treatments may contribute to the conservative surgery in preservation of ovarian reserve and tubal structure.en_US
dc.identifier.endpage289en_US
dc.identifier.issn0884-6812
dc.identifier.issue5en_US
dc.identifier.pmid25804001
dc.identifier.startpage285en_US
dc.identifier.urihttps://hdl.handle.net/11468/21969
dc.identifier.volume36en_US
dc.identifier.wosWOS:000349428100006
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSci Printers & Publ Incen_US
dc.relation.ispartofAnalytical and Quantitative Cytology and Histology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAdnexal Torsionen_US
dc.subjectFallopian Tubeen_US
dc.subjectIschemiaen_US
dc.subjectOvarian Torsionen_US
dc.subjectReperfusionen_US
dc.subjectWistar Raten_US
dc.titleEffects of Adnexal Torsion on the Fallopian Tube in Rats A Histologic and Immunohistochemical Studyen_US
dc.titleEffects of Adnexal Torsion on the Fallopian Tube in Rats A Histologic and Immunohistochemical Study
dc.typeArticleen_US

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