Ultrastructural Effects of the Propineb on Brain of Fetuses During Rat Pregnancy

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dc.contributor.authorEkinci, C.
dc.contributor.authorTahaoglu, A. E.
dc.contributor.authorYavuz, D.
dc.contributor.authorDeveci, E.
dc.contributor.authorAktas, A.
dc.contributor.authorYilmaz, T.
dc.contributor.authorYumusak, O.
dc.date.accessioned2024-04-24T17:24:10Z
dc.date.available2024-04-24T17:24:10Z
dc.date.issued2014
dc.departmentDicle Üniversitesien_US
dc.description.abstractPropineb is a fungicide with a propylene-bis-dithiocarbamate structure. Pregnant Wistar rats were exposed to 400 ppm propineb concentrations in 5 ml distilled water, 5 days per week until the end of pregnancy. The rats were treated with propineb for 16 days and the brains of litter rats were sacrificed at first day of birth after which their brains were collected. Ultrastructural examination of the brains of the fetuses and propineb-treated pregnant females revealed a variety of histopathological effects. We suggest that mitochondrial damage may be an effective factor for neuron necrosis. These results supported the proposal that the exposure to fungicides such as propineb and to other naturally occurring compounds which inhibit mitochondrial function, may contribute to Parkinson's disease development.en_US
dc.identifier.doi10.4067/S0717-95022014000400054
dc.identifier.endpage1471en_US
dc.identifier.issn0717-9502
dc.identifier.issn0717-9367
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-84921758072
dc.identifier.scopusqualityQ3
dc.identifier.startpage1467en_US
dc.identifier.urihttps://doi.org/10.4067/S0717-95022014000400054
dc.identifier.urihttps://hdl.handle.net/11468/19482
dc.identifier.volume32en_US
dc.identifier.wosWOS:000348581400054
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherSoc Chilena Anatomiaen_US
dc.relation.ispartofInternational Journal of Morphology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPropineben_US
dc.subjectElectron Microscopyen_US
dc.subjectNeonatal Ratsen_US
dc.subjectBrainen_US
dc.titleUltrastructural Effects of the Propineb on Brain of Fetuses During Rat Pregnancyen_US
dc.titleUltrastructural Effects of the Propineb on Brain of Fetuses During Rat Pregnancy
dc.typeArticleen_US

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