Does neutrophil/lymphocyte ratio contribute to diagnostics in patients with fascioliasis?

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dc.contributor.authorÇiçek, Mutalip
dc.contributor.authorDeveci, Özcan
dc.contributor.authorCengiz, Zeyneptaş
dc.contributor.authorBilden, Alican
dc.contributor.authorBilik, Özge Alkan
dc.date.accessioned2024-04-24T17:56:51Z
dc.date.available2024-04-24T17:56:51Z
dc.date.issued2018
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Mikrobiyoloji Ana Bilim Dalıen_US
dc.description.abstractIntroduction: Fasciolia sp. is a trematode causes infection by settling in the liver bile ducts of domestic animal and human liver. Fascioliasis is a parasite disease that might have changes in liver parenchyma and in bile ducts. Many inflammatory reactions occur during the settlement of larvae and mature parasites into the liver. The neutrophil/lymphocyte ratio (NLR) has become a prominent marker of underlying inflammation. The objective of the present study is to investigate the relationship between the hematological parameters in patients with fascioliasis. Materials and methods: The diagnosis of fascioliasis was based on patient history, clinical and laboratory findings, radiological imaging (ultrasound), stool examination and IgG antibody titer determination by ELISA. Clinical and laboratory data were collected for 56 patients with fascioliasis, and diagnosed with serological and radiological imaging. 56 healthy volunteers were selected for the control group. Stool and blood samples were collected from patients with fascioliasis for serologic, biochemical, hematologic tests and ova examination. Total leukocyte, neutrophil, eosinophil and lymphocyte counts were recorded and NLR was calculated. ELISA antibody cut off titer value of patients with fascioliasis was 10> positive. Results: We compared neutrophil/lymphocyte ratio, eosinophil/lymphocyte ratio, the relation of eosinophilia and IgG antibody titers between two groups (patient and control groups). There was no statistically significant difference between patients and healthy controls neither based on age and gender nor NLR. According to these findings, NLR can not be considered as a diagnostic marker in fascioliasis. Conclusion: As a result, it was determined that NLR is not a crucial indicator of inflammation in parasitic fascioliasis. Extensive studies are need to be done to clarify the correlation between NLR and progression of other parasitic diseases.en_US
dc.identifier.citationÇiçek, M., Deveci, Ö., Cengiz, Z., Bilden, A. ve Bilik, Ö. A. (2018). Does neutrophil/lymphocyte ratio contribute to diagnostics in patients with fascioliasis?. Acta Medica Mediterranea, 34(4), 955-958.
dc.identifier.doi10.19193/0393-6384-2018-4-145
dc.identifier.endpage958en_US
dc.identifier.issn0393-6384
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-85061457339
dc.identifier.scopusqualityN/A
dc.identifier.startpage955en_US
dc.identifier.urihttps://doi.org/10.19193/0393-6384-2018-4-145
dc.identifier.urihttps://hdl.handle.net/11468/23691
dc.identifier.volume34en_US
dc.identifier.wosWoSIDEksik
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherA. CARBONE Editoreen_US
dc.relation.ispartofActa Medica Mediterranea
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectContribution to diagnosisen_US
dc.subjectFascioliasisen_US
dc.subjectNeutrophil/Lymphocyte ratioen_US
dc.titleDoes neutrophil/lymphocyte ratio contribute to diagnostics in patients with fascioliasis?en_US
dc.titleDoes neutrophil/lymphocyte ratio contribute to diagnostics in patients with fascioliasis?
dc.typeArticleen_US

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