Serum prolidase activity in benign joint hypermobility syndrome

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dc.contributor.authorEm, Serda
dc.contributor.authorUçar, Demet
dc.contributor.authorOktayoǧlu, Pelin
dc.contributor.authorBozkurt, Mehtap
dc.contributor.authorÇağlayan, Mehmet
dc.contributor.authorYıldız, İsmail
dc.contributor.authorEvliyaoğlu, Osman
dc.contributor.authorNas, Kemal
dc.date.accessioned2024-04-24T17:56:34Z
dc.date.available2024-04-24T17:56:34Z
dc.date.issued2014
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Fizik Tedavi ve Rehabilitasyon Ana Bilim Dalıen_US
dc.description.abstractBackground: Moderate joint laxity is widespread in many joints of he body, and this condition is considered to be caused by an abnormality in the collagen structure. This study was carried out to determine the serum prolidase activity in female patients with benign joint hypermobility syndrome (BJHS), and to evaluate its correlation with their clinical features. Methods. A total of 45 patients with BJHS and 40 healthy controls were included in the study. All of the patients with BJHS met the Beighton diagnostic criteria. All the patients and the control group underwent a comprehensive examination of the locomotor system and took the New York Posture Rating Test. The examination and test results were recorded. Serum prolidase activity was measured in both the groups. Results: Prolidase activity was significantly lower in patients with BJHS (479.52 ± 126.50) compared to the healthy controls (555.97 ± 128.77) (p = 0.007). We found no correlation between serum prolidase activity and Beighton scores or New York rating test scores. On the other hand, mean prolidase activity was significantly lower in patients with pes planus or hyperlordosis compared to those without (p = 0.05, p = 0.03, respectively). We did not find such a correlation with the other clinical features. Conclusions: Significantly lower prolidase activity in patients with BJHS suggests that prolidase may affect the collagen metabolism and cause hyperlaxity.en_US
dc.identifier.citationEm, S., Uçar, D., Oktayoǧlu, P., Bozkurt, M., Çağlayan, M., Yıldız, İ. ve diğerleri. (2014). Serum prolidase activity in benign joint hypermobility syndrome. BMC Musculoskeletal Disorders, 15(1), 1-5.
dc.identifier.doi10.1186/1471-2474-15-75
dc.identifier.issn1471-2474
dc.identifier.issue1en_US
dc.identifier.pmid24612543
dc.identifier.scopus2-s2.0-84899424197
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.1186/1471-2474-15-75
dc.identifier.urihttps://hdl.handle.net/11468/23575
dc.identifier.volume15en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherBioMed Central Ltd.en_US
dc.relation.ispartofBMC Musculoskeletal Disorders
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHypermobilityen_US
dc.subjectLigamenten_US
dc.subjectNew York rating testen_US
dc.subjectProlidaseen_US
dc.titleSerum prolidase activity in benign joint hypermobility syndromeen_US
dc.titleSerum prolidase activity in benign joint hypermobility syndrome
dc.typeArticleen_US

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