2015-2017 yılları arasında izole edilen citrobacter suşlarında antibiyotik direnci
Yükleniyor...
Tarih
2017
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Antibiyotik ve Kemoterapi Derneği
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Bu çalışmada Nisan 2015-Mart 2017 tarihleri arasında infeksiyon etkeni olarak izole edilen Citrobacter suşlarının antibiyotik dirençlerinin belirlenmesi amaçlanmıştır. İzole edilen 72 Citrobacter suşundan 37'si Citrobacter freundii 35'i diğer Citrobacter türleri olarak identifiye edilmiştir. İzole edilen suşların farklı antimikrobiyallere minimum inhibitör konsantrasyon değerleri incelenmiş ve ampisiline % 99, seftazidime % 25, aztreonam ve trimetoprim/sülfametoksazole % 22, siprofloksasine % 15, piperasilin/tazobaktam ve gentamisine % 11, sefepime % 10, meropeneme % 1 ve amikasine % 0 oranlarında direnç saptanmıştır. Amikasin ve meropenem en etkili antibiyotikler olarak bulunmuş, bunları sefepim, gentamisin ve piperasilin/tazobaktam izlenmiştirÇalışmada amikasin ve meropenemin Citrobacter infeksiyonları için iyi bir tedavi alternatifi olduğu sonucuna varılmıştır.
Antibiotic Resistance of Citrobacter Strains Isolated Between 2015 and 2017Citrobacter is a group of bacteria that causes hospital-acquired infections mostly in newborn and immunosuppressed patients. The aim of this study to antibiotic resistance of Citrobacter strains isolated from clinical specimens between April 2015 and March 2017 as infection agents. 37 C.freundii and 35 other Citrobacter strains, totally 72 Citrobacter strains were isolated. When MIC values of isolates were taken into consideration altogether, rate of resistance were as follows: 99 % to ampicillin, 25 % to ceftazidime, 22 % to trimethoprim/sulfamethoxazole and aztreonam, 15 % to ciprofloxacin, 11 % to piperasillin/tazobactam and gentamisin, 10 % to cefepime, % 1 to meropenem and % 0 to amikacin, amikacin and meropenem are determined that the most efficient antibiotics, these antibiotics were followed by cefepime, gentamisin and piperasillin/tazobactam against to Citrobacter strains. It has been concluded that amikacin and meropenem are good treatment alternatives for Citrobacter infections in our study.
Antibiotic Resistance of Citrobacter Strains Isolated Between 2015 and 2017Citrobacter is a group of bacteria that causes hospital-acquired infections mostly in newborn and immunosuppressed patients. The aim of this study to antibiotic resistance of Citrobacter strains isolated from clinical specimens between April 2015 and March 2017 as infection agents. 37 C.freundii and 35 other Citrobacter strains, totally 72 Citrobacter strains were isolated. When MIC values of isolates were taken into consideration altogether, rate of resistance were as follows: 99 % to ampicillin, 25 % to ceftazidime, 22 % to trimethoprim/sulfamethoxazole and aztreonam, 15 % to ciprofloxacin, 11 % to piperasillin/tazobactam and gentamisin, 10 % to cefepime, % 1 to meropenem and % 0 to amikacin, amikacin and meropenem are determined that the most efficient antibiotics, these antibiotics were followed by cefepime, gentamisin and piperasillin/tazobactam against to Citrobacter strains. It has been concluded that amikacin and meropenem are good treatment alternatives for Citrobacter infections in our study.
Açıklama
Anahtar Kelimeler
Antibiyotik direnci, Citrobacter, Antibitic resistance
Kaynak
ANKEM Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
31
Sayı
3
Künye
Atmaca, S., Özekinci, T., Yakut, S., Akpolat, N. ve Gül, K. (2017). 2015-2017 yılları arasında izole edilen citrobacter suşlarında antibiyotik direnci. ANKEM Dergisi, 31(3), 79-84.
