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Öğe Bifid uvula and submucous cleft palate in cornelia de lange syndrome(2011) Callea M.; Montanari M.; Radovich F.; Clarich G.; Yavuz I.Cornelia de Lange syndrome is a rare congenital disease characterized by growth and psychomotor retardation, peculiar facial feature as skeletal and craniofacial deformities, gastrointestinal and cardiac problems and malformation of the upper limb. The prevalence is estimated around 0.6/100000 in the population1. The diagnosis is based on clinical findings and the etiology is still unclear. We present a case of a 17-year-old patient, who came to our attention for dental pain. After an oral examination carried out under general anesthesia the patients presented most of the charactericts described in the literature as micrognathia, high arched palte, delayed aruption, missing of some teeth. The most peculiar findings were the bifid uvula and the submucous cleft palate. The entity of clefting can be determined only with a Magnetic Resonance Imaging which should be carried out under general anesthesia. Caries and periodontal disease were present and the entire dental treatment has been carried out in one sitting without any anestesiologic problems2-5.Öğe A c.3037G>a mutation in FBN1 gene causing marfan syndrome with an atypically severe phenotype(Instituto de Investigaciones Clinicas, 2017) Callea M.; Willoughby C.E.; Camarata-Scalisi F.; Giovannoni I.; Vinciguerra A.; Yavuz I.; Di Stazio M.Marfan syndrome is a pleiotropic connective tissue disease inherited as an autosomal dominant trait, mostly caused by mutations in the FBN1 gene, which is located on chromosome 15q21.1 and encoding fibrillin 1. We report a case of Marfan syndrome presenting with severe ocular and systemic manifestations, such as cardiac congenital anomalies. The patient underwent a multidisciplinary approach and his clinical diagnosis was associated with a c.3037G>A mutation in the FBN1 gene. Identification of this genetic alteration should instigate a prompt multidisciplinary assessment and monitoring, in order to prevent devastating consequences such as cardiac and ocular phenotype. Molecular modeling of the mutation highlighted the importance of the preservation of the calcium-dependent structure of an epidermal-growth-factor-like domain of fibrillin-1 and consequently the microfibrillar formation process. This report aims to highlight the importance of an early clinical and molecular diagnosis and once more, the importance of the multidisciplinary approach of this genetic entity. © 2017, Instituto de Investigaciones Clinicas. All rights reserved.Öğe A case of Beckwith- Wiedemann syndrome with peculiar dental findings(Ariesdue Srl, 2016) Callea M.; Yavuz I.; Clarich G.; Gunay A.; Vinciguerra A.; Unal M.; Sahbaz C.Background Beckwith-Wiedemann syndrome (BWS, OMIM 130650) is a rare genetic disorder characterised by overgrowth, tumor predisposition and congenital malformations. Few systemic manifestations and oral features have been reported so far. Case report We report on a case of BWS, describing all features expanding the knowledge on oro-dentofacial phenotypes, along with a review of the literature.Öğe Effects of radiofrequencies emitted from mobile phones on teeth and oral tissues(University of Dicle, 2017) Dasdag S.; Yavuz I.; Akdag M.Z.Number of various sources of wireless communication is had been incredibly increased in the recent decade. One of the most popular wireless communication equipment is mobile phones. However, another widespread part of wireless communications is Wi-Fis. As it is known, smart phones has many function such as speaking, Wi-Fi, bluetooth etc. Therefore, their radiofrequency radiation (RFR) level is higher than the first generation mobile phones. It means that smart phones emit higher RFR. The results of studies performed on the effects of RFR on animal or human indicated that mobile phones are not innocent. Because of that RFRs classified as 2B (Possible carcinogen) by World Health Organization in 2011. Most of the studies usually performed on RFR and health focused on the brain tumors and other diseases. No one pay attention to the potential health effects of this electromagnetic pollutant on oral tissues and teeth, which are one of the most RFR exposed parts of heads at the beginning. Although limited number of the studies had been done on oral tissues, the results of the studies are worth considering. Therefore, the aim of this review is to summarize the results of the limited studies here. In conclusion, the results of the studies investigated the effects of RF exposure on oral tissues and teeth indicated that uncontrolled exposures may have potential to cause some dental health problems. Finally, further studies including human studies are necessary to illuminate this topic.Öğe ELF electromagnetic field and strontium ranilate influences on the trace element content of rat teeth(2009) Kaya S.; Akdag M.Z.; Yavuz I.; Celik M.S.; Adiguzel Ö.; Tumen E.C.; Kaya F.A.Exposure to Extremely Low Frequency (ELF) Electromagnetic Field (EMF) emanating from the generation, distribution and utilization of electricity. The major debate in recent years has focused on the possibility that exposure to EMF may result some health consequences such as differentiation on bone constitute. In this study, the effect of ELF-EMFs and strontium ranelate on teeth constitute amount of mineral were investigated in rats. Seventy-five four month old adult female Sprague-Dawley rats were randomly divided into 5 different groups (n = 15). After all applications, some mineral levels such as: Ca, Mg and Zn in rat teeths were determined with Atomic Absorbtion Spectrophotometry (AAS) and the phosphorus content of teeth was determined by Ultraviolet Spectrophotometer (UVS). It was determined that the levels of Ca and P were not statistically different in comparison to Cg-Cnt and between groups (p>0.05). However, it was observed that the levels of Zn significantly alterations between some groups (p<0.05). The levels of Mg in ELF-EMF+OVX, ELF-EMF and OVX groups decreased significantly in comparison to Cg-Cnt group (p<0.05). As a resulf it can be suggested that mineral amount of rat teeth can change after ovariectomy and ELF-EMF exposure, also strontium ranelate treatments can't increase mineral amount of teeth. © Medwell Journals, 2009.Öğe Evaluation of root fracture in permanent teeth according to season(Polskie Towarzystwo Stomatologiczne, 2017) Dogan M.S.; Kusdhany L.S.; Maharani D.A.; Callea M.; Yavuz I.Aim of the study. Root fractures which occur as a result of dental trauma may change according to school and holiday periods, and seasons. The aim of our study was to evaluate their incidence as dental trauma based on seasonal variation in children between 8-15 years of age. Material and method. This epidemiological study was performed on 76 children patients who sustained root fracture. Root fractures were diagnosed using cone beam computed tomography and conventional radiography. The incidence of root fracture was examined and compared according to the seasons when patients presented for treatment. The study' data were applied to chi-square test. Results. As a result of our study, it was found that root fractures often occur in winter and in males rather than females. When the distribution of root fractures in boys and girls is examined according to season, it is noted that. © 2017 Polish Dental Association.Öğe HED (Hypohidrotic Ectodermal Dysplasia): A Review(University of Dicle, 2021) Callea M.; Scalisi F.C.; Yavuz I.; Dogan M.S.; Willoughby C.E.; Bashyam M.D.Abstract The ectodermal dysplasias (EDs) are a heterogeneous group of inherited, developmental disorders characterized by alterations in two or more ectodermal structures including the hair, teeth, nails and sweat glands. Currently, more than 200 types of ectodermal dysplasias have been described. Anhidrotic or hypohidrotic ectodermal dysplasia (AED/HED), the most common ED, is characterized by three cardinal features: hypotrichosis, hypohidrosis and hypodontia. We review the genetic and pathogenetic mechanisms of AED/HED and report on the management of clinical manifestations driven by embryology, anatomy and physiology. © 2021, Journal of International Dental and Medical Research, All Rights Reserved.Öğe An interdisciplinary approach in a patient with amelogenesis imperfecta: A clinical report and literatüre review(2012) Ulku S.Z.B.; Callea M.; Yavuz I.; Clarich G.; Kaya F.A.; Maglione M.; Kaya S.This clinical report describes an interdisciplinary approach for the coordinated treatment of a 20-year-old woman patient diagnosed with amelogenesis imperfecta. The treatment objective was to restore masticatory function, to reduce dental sensitivity and improve the facial esthetics. A multidisciplinary team approach treatment is recommended, including periodontology, orthodontics, endodontics, and prosthodontics. Prosthodontic treatment included composite laminate veneers and metal-ceramic fixed partial dentures. After treatment the patient was regularly recalled during the 25-months postoperative period. Radiographic and clinical examinations at recall revealed no evidence of complications associated with the restored teeth or their supporting structures.Öğe New direction for measurement of microleakage in cariology research(2010) Yavuz I.; Aydin H.The present study introduces the feasibility of a different new direction to determining the microleakage volume associated with dental restorations and the relative marginal adaptation deficiency of teeth in in vitro conditions. Our method utilizes the molecular adsorption characteristics of Methylene Blue. It was concluded that investigations showed the microleakage volume measurement method looking as a valuable new technique for the in vitro study of microleakage dynamics around dental restorations.Öğe The prevelance and etiology of dental trauma among 5-72 months preschool children in South-Eastern Anatolia, Turkey(2009) Tumen E.C.; Adiguzel O.; Kaya S.; Uysal E.; Yavuz I.; Atakul F.The main objective of this study was to assess the epidemiology of traumatic dental injuries to the primary teeth in children from 5 to 72 months, all atendees in 11 public nursery schools in South-Eastern Anatolia, Turkey. A total of 657 children (346 boys and 311 girls) of both sexes participated in the study. Traumatic dental injuries were classified according to the modified classification proposed by Ellis. An interview was carried out by two trained and calibrated examiners, and clinical oral examinations included distribution of dental injuries by age and sex, etiology of dental trauma, prevelance of affected teeth and type of damage. All results were analyzed using the Statistical Package for Social Sciences (SPSS) software, version 15.0. The prevalence of traumatic dental injuries was 5.02%. There was greater involvement of boys (78.8%), of children aged 37-48 months (63.63%) and of the maxillary central incisors (92.68%). Falls were more often the etiology for dental injuries (66.7%). Most children with a traumatic dental injuries experienced traumatic injuries to one tooth (3.81%), while 1.21% had two traumatized teeth and 94.9% had no traumatic dental injuries. The most common crown fracture was in enamel only (65.9%), followed by discoloration teeth (14.6%). The prevalence of dental injuries in Turkish preschool children was very low. The present study findings emphasize the importance of encouraging parents to visit the dentist with their child at an early stage. Moreover, traumatic dental injury is widespread in the population; it has both physical and psychological effects, it is treatable; and, most importantly, it is preventable.Öğe The relation of follicle stimulating hormone and estrogen to mandibular alveolar bone resorption in postmenopausal women(University of Dicle, 2017) Puspitadewi S.R.; Wulandari P.; Masulili S.L.C.; Auerkari E.I.; Iskandar H.B.; Yavuz I.; Kusdhany L.S.Osteoporosis is one of the degenerative disorders characterized by the bone mass reduction due to an imbalance between bone resorption and formation. Osteoporosis is common in postmenopausal women. Increased FSH (Follicle Stimulating Hormone) hormones and decreased estrogen levels occur post menopause, leading to the increased bone resorption rate. The aim of this study is to analyze the relation of FSH and Estrogen hormone to the mandibular alveolar bone resorption in postmenopausal women. Seventy postmenopausal women aged 48-87 years in Kenari sub-district, Central Jakarta between February - May 2017 participated in this study. After obtaining the research approval from the ethics commission and informed consent from the subjects, the participants then filled out a validated questionnaire, and a clinical examination was performed. The periapical radiography was taken by referral to the Department of Radiology Universitas Indonesia to assess the radiographic bone resorption rate. Blood samples were taken to assess the FSH and Estradiol levels by ELISA examination technique. The result of this study showed that bone density correlated with age (p=0.01) and estrogen (p=0.02) but there was no correlation with bone resorption and FSH (p > 0.05). The conclusion of this study, there was a significant association between age and estrogen to the bone density of postmenopausal women. However, no association was found between FSH and bone resorption to the bone density of postmenopausal women. © 2018 Journal of International Dental and Medical Research.Öğe Syndromic craniosynostosis: A review(University of Dicle, 2016) Cammarata-Scalisi F.; Ozen B.; Chacín J.A.; Yavuz I.; Callea M.Craniosynostosisis a defect of the skull caused by premature fusion of one or more cranial sutures. It may be isolated finding or part of a syndrome and affects 1 in every 2,500 live births.Usually multiple sutures are involved and correspond in at least 20% of the cases. Syndromic craniosynostosis can be associated with various dysmorphic features involving the face, skeleton and nervous system. More than 180 syndromes have been reported with craniosynostosis.The aim of this review is to present the clinical and genetic characteristics of the most common types of syndromiccraniosynostosis.Öğe An unusual case: Neurofibromatosis type 5(2012) Callea M.; Ulku S.Z.B.; Giustini S.; Yavuz I.; Ulku M.M.; Montanari M.; Basaran G.Neurofibromatosis is a disease which includes 5 types in its classification. It has been firstly described by Robert Smith in 1849, but its name comes from the first publication in 1882, in which Von Recklinghausen convinced the scientific and medical world that Neurofibromatosis (NF) was a distinct entity. Cafe-au-lait spots, cutaneous neurofibromas and Lisch nodules are the characteristics of the most common forms. Bilateral acoustic neuromas distinguish the type 2. Type 3, Riccardi type and intestinal type are briefly described. Neurofibromatosis type 5 (NF5) is characterized by cafe-au-lait spots restricted to one area of the body. We report oro-dental phenotype of a patient affected by NF type 5, rare per se and unreported in literature.
