The relation of follicle stimulating hormone and estrogen to mandibular alveolar bone resorption in postmenopausal women

Osteoporosis is one of the degenerative disorders characterized by the bone mass reduction due to an imbalance between bone resorption and formation. Osteoporosis is common in postmenopausal women. Increased FSH (Follicle Stimulating Hormone) hormones and decreased estrogen levels occur post menopause, leading to the increased bone resorption rate. The aim of this study is to analyze the relation of FSH and Estrogen hormone to the mandibular alveolar bone resorption in postmenopausal women. Seventy postmenopausal women aged 48-87 years in Kenari sub-district, Central Jakarta between February - May 2017 participated in this study. After obtaining the research approval from the ethics commission and informed consent from the subjects, the participants then filled out a validated questionnaire, and a clinical examination was performed. The periapical radiography was taken by referral to the Department of Radiology Universitas Indonesia to assess the radiographic bone resorption rate. Blood samples were taken to assess the FSH and Estradiol levels by ELISA examination technique. The result of this study showed that bone density correlated with age (p=0.01) and estrogen (p=0.02) but there was no correlation with bone resorption and FSH (p > 0.05). The conclusion of this study, there was a significant association between age and estrogen to the bone density of postmenopausal women. However, no association was found between FSH and bone resorption to the bone density of postmenopausal women. © 2018 Journal of International Dental and Medical Research.