Yazar "Kayabasi, Hasan" seçeneğine göre listele
Listeleniyor 1 - 20 / 30
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe The association of demographic, clinical, and thrombophilic factors with the failure of arteriovenous fistula among hemodialysis patients(Saudi Med J, 2008) Kadiroglu, Ali K.; Sit, Dede; Kayabasi, Hasan; Yilmaz, Zulfukar; Yilmaz, EminObjective: To evaluate the association of demographic, clinical, and thrombophilic factors with the failure of arteriovenous fistula (AVF) among patients undergoing chronic hemodialysis. Methods: Sixty-two (33 males, 29 females) patients undergoing chronic hemodialysis were included in the study in March 2005 at the Hemodialysis Center of the Medicine Faculty at Dicle University, Diyarbakir, Turkey. The patients were divided into 2 groups according to whether they needed (group II) or do not need (group 1) more than one fistula placed. Results: Female gender, longer vintage of hemodialysis, frequent intradialytic hypotensive episodes, elevated levels of phosporous, calcium-phosporous product (Cap), and intact parathormone (iPTH), and left ventricle hypertrophy were more likely in group 2. Conclusion: Arteriovenous fistula loss, and recurrent requirement of AVF constitution increase with hemodialysis vintage. We believe that female gender, frequent intradialytic hypotensive episodes, elevated serum levels of phosporous, iPTH, and high Cap products are risk factors related to the failure of AVF among hemodialysis patients.Öğe AN ATYPICAL LOCALISATION OF TUBERCULOSIS INFECTION IN PATIENTS UNDERGOING HAEMODIALYSIS: A CASE REPORT(Wiley, 2010) Kayabasi, Hasan; Sit, Dede; Kadiroglu, Ali Kemal; Yilmaz, Zulfukar; Bukte, YasarSpinal tuberculosis (TB) is a rare skeletal system localisation of TB in haemodialysis patients. In this paper, a case of Pott's disease with a psoas muscle abscess is reported. The patient had been on the dialysis programme for five years and was complaining of back pain, weight loss and weakness, which were investigated. A thoracolumbar magnetic resonance imaging showed multiple paravertebral abscesses invading the psoas muscle. TB diagnosis was made by microbiological analysis of specimen, which was obtained by fine needle aspiration under computerised tomography guidance.Öğe Bilateral complete optic atrophy and hemorrhagic infarction of the putamen caused by methanol intoxication(Humana Press Inc, 2007) Ari, Seyhmus; Caca, Ihsan; Kayabasi, HasanMethanol is a potent toxic substance for the optic nerves. Even small amounts of ingested methanol can acute permanent neurological dysfunction and irreversible blindness. Methanol intoxication can cause severe visual dysfunction and death. We present a case of a 25 years old admitted to our clinic with bilateral optical atrophy after drinking eau de cologne.Öğe Carpal Tunnel Syndrome Based on Accumulation of ?2 Microglobulin With Vascular Steal Syndrome: A Case Report(Turk Nefroloji Diyaliz Transplantasyon Dergisi, 2006) Kadiroglu, Ali Kemal; Sit, Dede; Kayabasi, Hasan; Yilmaz, M. Emin; Isikoglu, BunyaminRheumatologic and osteoarticular syndromes occur frequently in chronic haemodialysis patients. The number and severity of these complications increase with the time on hemodialysis (HD). Beta-2 microglobulin accumulates in the soft tissue in HD patients due to its low level of clearance. Carpal tunnel syndrome (CTS) is one of the clinical expressions of this accumulation. Early diagnosis and treatment of CTS is important, since being late may lead to permanent defect and/or resistant symptoms.Öğe Comparison of the effects of Losartan and Nebivolol on oxidative stress in patients with end stage renal disease(Oxford Univ Press, 2007) Kayabasi, Hasan; Kadiroglu, Ali Kemal; Sit, Dede; Selek, Sahabettin; Yilmaz, M. Emin[Abstract Not Available]Öğe Delirium With a Single Dosage of Acyclovir in a Continuous Ambulatory Peritoneal Dialysis Patient: Case Report(Turk Nefroloji Diyaliz Transplantasyon Dergisi, 2007) Kayabasi, Hasan; Kadiroglu, Ali Kemal; Kara, Ismail Hamdi; Sit, Dede; Yilmaz, M. EminValacyclovir is an effective oral agent for the treatment of herpes virus infection, however, the pharmacokinetics of the drug are altered in renal failure. It is increasingly recognized that dose adjustment of oral valacyclovir in renal failure is necessary to avoid neurotoxicity. We studied this drug in a continuous ambulatory peritoneal dialysis (CAPD) and immunocompromised patient. She developed neurotoxicity with an adjustment dosage of valacyclovir for a cutaneous zoster infection. The elimination half-time (15 h) was similar to that reported for end-stage renal disease patients, while the steady-state volume of distribution (85 l) and the area under the curve concentration (127 mg/l.h) were greater. The mean CAPD dialysance was only 5.27 ml/min with less than 1% of an administered dose being recovered in the 24-hour dialysate. 48 h after interrupting treatment, she recovered normal neurological status and 500 mg of valacyclovir every 2 days was effective and well tolerated.Öğe The effect of inflammatory reactions on antibody unresponsiveness to hepatitis B vaccine in hemodialysis patients(Briefland, 2007) Sit, Dede; Kadiroglu, Ali Kemal; Kayabasi, Hasan; Yilmaz, Zuelfuekar; Yilmaz, Mehmet EminBackground and Aims: In this study, the effect of infections and inflammation developed during hepatitis B vaccination program on antibody response in hemodialysis (HD) patients was evaluated. Methods: In total, 94 patients who had hepatitis B surface antigen (HBsAg) (-), antibody to hepatitis B surface (antiHBs) (-), antibody against hepatitis B core immunoglobulin G (antiHBclgG) (-) (Group A) and who were previously vaccinated but having antibody titer levels lower than 10 mIU/mL (Group B), on maintenance HD program were included in this study. In group A, 40 mu g intramuscular vaccine on 0, 1, 2 and 6 months and in group B, 40 mu g of intramuscular booster dose vaccine were administered. Antibody titer of 10 mIU/mL was considered as positive. Group A was then divided into two subgroups with respect to antibody response (Group A1 and Group A2). Results: Eighty-one patients completed the study (Group A; n=64, mean age=42.3 +/- 11.4 years; Group B: n=17, mean age=53.6 +/- 10.6 years). In Group A, antibody response was positive in 82.8% (Group A1), negative in 17.2% (Group A2) and it was positive in 100% of Group B. Inflammatory parameters, nutritional and demographic features were found similarly in all groups. Throughout the study, infections developed most frequently in Group A. Conclusions: We concluded that acute infections and inflammations developed in patients vaccinated according to vaccination schedule recommended for HBV prophylaxis during HD treatment does not affect antibody response and acute phase reactants are not indicators for negative antibody response.Öğe The effect of venlafaxine HCl on painful peripheral diabetic neuropathy in patients with type 2 diabetes mellitus(Elsevier Science Inc, 2008) Kadiroglu, Ali Kemal; Sit, Dede; Kayabasi, Hasan; Tuzcu, Alpaslan Kemal; Tasdemir, Nebahat; Yilmaz, M. EminObjective: The objective of this study was to evaluate the efficacy of venlafaxine HCl in the symptomatic treatment of painful peripheral diabetic neuropathy (PPDN) among patients with type 2 diabetes mellitus (DM). Design: This study was designed as a prospective, randomized, and controlled trial. Setting: This study was conducted at the Dicle University Medical Faculty (Diyarbakir, Turkey). Patients: Sixty type 2 DM outpatients (47 females and 13 males) with PPDN who had a minimum visual analog scale (VAS) score of 40 mm were enrolled in this study. Interventions: Patients randomized to the treatment group (n=30) received venlafaxine HCl, whereas those randomized to the control group (n=30) received a combination of vitamins B-1 and B-6 tablets. Measures: Severity of pain was measured by VAS, Short-Form McGill Pain Questionnaire, and numerical analog scale scores at admission and at the second, fourth, and eighth weeks of the study. Polyneuropathy was supported by electromyelography. Outcome: In the treatment group, severity of pain was measured as 70.0+/-13.0 in the VAS, as 24.9+/-6.2 in the Short-Form McGill Pain Questionnaire, and as 7.2+/-1.1 in the numerical analog scale. In the control group, it was measured as 73.0+/-8.0 in the VAS, as 26.8+/-6.2 in the Short-Form McGill Pain Questionnaire, and as 7.4+/-0.8 in the numerical analog scale (P>.05). Results: The most common form of PPDN was distal symmetrical sensorimotor polyneuropathy in both groups (46.8% vs. 50.0%). At the end of the study, there was a significant difference in severity of pain between the groups. In the treatment group, scores were 8.5+/-5.2 and 3.1+/-1.6 in the Short-Form McGill Pain Questionnaire and numerical analog scale, respectively; in the control group, these were 20.5+/-7.0 and 5.5+/-1.6, respectively (P<.001). Conclusions: Venlafaxine HCl is a safe and well-tolerable analgesic drug in the symptomatic treatment of PPDN; however, it has minimal adverse effects. It showed its efficacy markedly in the second week of therapy. (C) 2008 Elsevier Inc. All rights reserved.Öğe The effects of losartan on the oxidative stress index and thiols in patients undergoing dialysis treatment(Oxford Univ Press, 2007) Kadiroglu, Ali Kemal; Kayabasi, Hasan; Sit, Dede; Kara, I. Hamdi; Yilmaz, M. Emin[Abstract Not Available]Öğe The effects of nebivolol on serum levels of malonyldialdehyde and paraoxonase in patients with end stage renal disease(Oxford Univ Press, 2007) Sit, Dede; Kayabasi, Hasan; Kadiroglu, Ali Kemal; Yilmaz, Zulfikar; Yilmaz, M. Emin[Abstract Not Available]Öğe Eivaluation of the Nutritional Status and Anthropometric Measurements in Continuous Ambulatory Peritoneal Dialysis (CAPD) Patients According to the Anemia Status(Turk Nefroloji Diyaliz Transplantasyon Dergisi, 2007) Kadiroglu, Ali Kemal; Sit, Dede; Kayabasi, Hasan; Yilmaz, Zulfukar; Yilmaz, M. EminNutritional biochemical markers such as serum albumin and anthropometric measurements such as BMI are valid and useful tools in assessing the nutritional status in dialysis. Forty-two patients on CAPD therapy were enrolled in the study. Anemic patients and patients who were al target hematocrit levels were evaluated by nutritional parameters and anthropometry. Gender, age, duration of CAPD, dialysis adequacy, educational and economic status had significant affect on BMI and serum albumin. There were positive significant correlations between hematocrit levels and BMI (r=0.331, p=0.0032), and FM (r=.0.383, p=0.012), and MAMC (r=0.365, p=0.017I and serum albumin levels (r=0.416. p=0.006). Achieving target hematocrit levels may improve BMI and MAMC, but not biochemical parameters.Öğe The evaluation incidence and risk factors of mortality among patients with end stage renal disease in Southeast Turkey(Taylor & Francis Ltd, 2008) Sit, Dede; Kadiroglu, Ali Kemal; Kayabasi, Hasan; Kara, Ismail Hamdi; Yilmaz, Zulfukar; Yilmaz, M. EminAim. End stage renal disease (ESRD) presents with higher morbidity and mortality with respect to the general population. In recent study, the causes of mortality and associated risk factors in ESRD have been evaluated. Materials and Methods. In this study, 1538 patients diagnosed with ESRD in 10-year period were evaluated retrospectively. The patients were divided as dead (group 1) and alive (group 2). The patients' demographic features, causes of death, comorbidity at hospitalization, hematological and biochemical analyses, creatinine clearance at the beginning of hospitalization, daily urine volume, blood gas results, CRP value as inflammatory marker, ejection fraction, interventricular septum diameter, left ventricle posterior wall end-diastolic diameter, and left atrium diameter determined with echocardiography were recorded. Results. Mortality ratio of ESRD patients in a 10-year period was 14.1%. While the general mean age of all patients was 54.7 +/- 16.6 and male/female ratio was 781/757, these ratios were 66.3 +/- 21.8 and 114/103 in Group 1 and 52.8 +/- 21.7 and 667/654 in Group 2. One or more comorbid pathologies were present in 82.9% of Group 1. The most common cause of mortality was cardiovascular diseases (CVD), and the most common cause of comorbidity was infections. Older age, anemia, absence of residual renal function, hypoalbuminemia, inflammation, impaired Ca and P metabolism, and left ventricular hypertrophy were significantly higher in Group 1 than in Group 2. Conclusion. CVD are the most important preventable causes of morbidity and mortality in all stages of chronic kidney disease. Taking precaution against CVD and the associated complications will provide a positive contribution in reducing morbidity and mortality among ESRD patients.Öğe The evaluation of effects of demographic features, biochemical parameters, and cytokines on clinical outcomes in patients with acute renal failure(Taylor & Francis Ltd, 2007) Kadiroglu, Ali Kemal; Sit, Dede; Atay, A. Engin; Kayabasi, Hasan; Altintas, Abdullah; Yilmaz, M. EminAim. To evaluate the effects of cytokines, biochemical parameters and demographic features on clinical outcomes of acute renal failure (ARF). Patients and Methods. 59 patients with acute renal failure (28 men, 31 women) were enrolled to the study. Cytokines, biochemical parameters, and complete blood count were measured. Patients were divided into two groups: as survivors (group 1, n = 46) and nonsurvivors (group 2, n = 13). Results. Mean age of patients were 52.3 +/- 17.9 years. 46 patients survived (77.9%) and 13 patients died (22. 1 %). There was a statistically significant relationship between IL-2R, IL-6, and TNF-oc levels and mortality rates (p = 0.004, p = 0.016, p = 0.020, respectively) and between TC levels and mortality rates (p = 0.041). In multivariable logistic regression analysis, the effects of proinflammatory cytokines (IL- I beta, IL-2R, IL-6, TNF alpha, CRP, and ESR) on the clinical outcomes in ARF was observed to be statistically significant (r = 0.341, p = 0.005). Conclusion. We realized that in totally demographic features (male gender, advanced age, poor nutritional status), biochemical parameters (TC, albumin, and hemoglobin) and cytokine levels (IL-2R, IL-6, TNF-oc), CRP and ESR may be predictive factors for mortality in patients with ARF.Öğe The Evaluation of the Association Between Serum Cholesterol Levels with Nutritional Parameters and Anthropometric Measures in Non-Diabetic Continuous Ambulatory Peritoneal Dialysis Patients(Turk Nefroloji Diyaliz Transplantasyon Dergisi, 2009) Sit, Dede; Kayabasi, Hasan; Kadiroglu, Ali Kemal; Yilmaz, M. EminWe evaluated the association of serum cholesterol levels with nutritional parameters and anthropometric measurements in non-diabetic patients undergoing continuous ambulatory peritoneal dialysis (CAPD) treatment. Thirty-nine (21 males, 18 females) patients were enrolled into the study. The patients were divided into two groups as group 1 (n=20, serum cholesterol >= 200 mg/dl), and group 2 (n=19, serum cholesterol < 200 mg/dl.) according to serum cholesterol levels. A positive correlation was found between serum levels of cholesterol and prealbumin (r=0.428, p=0.007), transferrin (r=0.322, p=0.046), triglyceride (r=0.537, p=0.001), LDLC (r=0.739, p<0.001), and HDL-C (r=0.454, p=0.004), and between BMI and FM (r=0.851, p<0.001), FFM (r=0.503, p=0.001), TBW (r=0.522, p=0.001) and MAMC (r=0.849, p<0.001). BIA in group 1 was higher than group 2 (p = 0.007). No statistical relation was found between serum cholesterol, and the anthropometric measurements. In conclusion, we found a positive correlation between serum cholesterol levels and prealbumin and transferrin but not in anthropometric measurements in CAPD patients. Further, large scale studies are needed to conclude an absolute judgement.Öğe Evaluation of the Frequency of QTc Dispersion and Its Relationship with Clinical and Laboratory Parameters in Dialysis Patients(Turk Nefroloji Diyaliz Transplantasyon Dergisi, 2013) Yilmaz, Zulfukar; Yildirim, Yasar; Yilmaz Aydin, Fatma; Aydin, Emre; Kadiroglu, Ali Kemal; Yilmaz, Mehmet Emin; Kayabasi, HasanOBJECTIVE: QTc dispersion is defined as the difference between the maximal and minimal correct QT interval on standard 12-lead ECG. Increased QTc dispersion has been reported in ESRD patients. In our study, we aimed to evaluate the frequency of QTc dispersion and its relationship between clinical and laboratory parameters in patients on regular dialysis programme. MATERIAL and METHODS: Sixty patients underwent dialysis ( 30 HD, 30 CAPD) and another 30 healthy subjects were enrolled into the study. The standard 12 lead ECGs were performed and QTcd was measured from all dialysis patients and control subjects. Blood samples were collected for the measurement of laboratory parameters. RESULTS: Dialysis patients showed significantly higher QTcd than control subjects (55.75 +/- 36.48 versus 28.73 +/- 28.27; p=0.001). Patients with QTcd > 50 ms had significantly higher SBP, urea and ferritin levels, but significantly lower iron binding capacity and calcium levels compared those with QTcd <= 50 ms(p<0.05). Positive correlations were found between QTcd and urea, ferritin and SBP levels, and inverse correlations with iron binding capacity level (p<0.05). CONCLUSION: The frequency of QTc dispersion was 40% among the dialysis patients. Although serum calcium was significantly lower in patients who had QTcd > 50 ms than QTcd <= 50 ms (p<0.05), there was no significant correlation between QTcd and calcium.Öğe The Frequency Of Metabolic Syndrome in Patients on Continuous Ambulatory Peritoneal Dialysis and the Association of Developing Metabolic Syndrome With Dialysis Duration(Turk Nefroloji Diyaliz Transplantasyon Dergisi, 2011) Kayabasi, Hasan; Yilmaz, Zulfukar; Yildirim, Idris; Yildirim, Yasar; Kadiroglu, Ali Kemal; Yilmaz, M. EminOBJECTIVE: To evaluate the characteristics of patients with metabolic syndrome, and the association of developing MS with peritoneal dialysis duration among patients undergoing continuous ambulatory peritoneal dialysis. MATERIAL and METHODS: Fifty-eight nondiabetic CAPD patients were evaluated. Biochemical parameters, blood pressure, length, weight, waist circumference, and body mass indexes were recorded. MS was determined using NCP-ATP III criteria. The patients were divided into 3 groups according to dialysis duration (Group 1: <= 60 months, Group 2: 61-120 months, Group 3: >= 121 months) and the frequency of MS was compared. RESULTS: Twenty-four of 58 patients were male, and MS was present in 22 (37.9%) patients. 14 (82.4%) of 22 patients with MS were female, (p=0.544). There was a statistically significant difference between patients with and without MS regarding age, BMI, waist circumference, PD duration, and triglyceride levels (p<0.05). 55% (n=32) of the patients were in group 1, 34.5% (n=20) in group 2, and 10.5% (n=6) in group 3 (p=0.092). The frequency of MS decreased with prolongation of dialysis duration (50% in group 1, 20% in group 2, and 33,3% in group 3) (p<0.001). CONCLUSION: The frequency of MS among our CAPD patients was 37.9% and it decreased with prolongation of dialysis duration. This result may suggest that alterations in metabolic state, and abandoning glucose-based PD solutions may improve MS criteria.Öğe Impact of Volume Status on Blood Pressure and Left Ventricle Structure in Patients Undergoing Chronic Hemodialysis(Informa Healthcare, 2011) Koc, Yener; Unsal, Abdulkadir; Kayabasi, Hasan; Oztekin, Erkan; Sakaci, Tamer; Ahbap, Elbis; Yilmaz, MurvetIn this study, we aimed to examine the impact of volume status on blood pressure (BP) and on left ventricular mass index (LVMI) in chronic hemodialysis (HD) patients. This study enrolled 74 patients (F/M: 36/38, mean age 53.5 +/- 15.3 years, mean HD time 41.5 +/- 41 months) that were on HD treatment for at least 3 months. Demographics, biochemical tests, hemogram and C-reactive protein levels, mean interdialytic weight gain (IDWG), mean percentage of ultrafiltration (UF), and intradialytic complications such as hypotension and cramps were determined. Mean values of predialysis and postdialysis BP measurements were recorded a month before echocardiographic examination. On the day after a midweek dialysis session, 24 h ambulatory BP monitoring (ABPM) and echocardiographic examination were made concurrently. The patients were classified into two groups according to volume status: normovolemic (group 1; 14F/24M, mean age 50 +/- 16.7 years, mean dialysis time 47.7 +/- 47.7 months) and hypervolemic (group 2; 15F/21M, mean age 57.3 +/- 12.7 years, mean dialysis time 34.9 +/- 32 months). HD duration, IDWG, UF, and interdialytic complication rates were similar between the two groups (p < 0.05). Eleven patients (28.9%) of group 1 and 8 patients (22.2%) of group 2 showed dipper (p = 0.50). Valvular damage was more common in group 2 (p = 0.002). Whereas 33 patients (91.7%) had left ventricular hypertrophy (LVH) in group 2, 21 patients of the group 1 (55.3%) had LVH (p < 0.001). Although LVMI showed a significant positive correlation with cardiothoracic index, predialysis and postdialysis BP, IDWG, UF, daytime and nighttime BP measurements of 24 h ABPM, a significant negative correlation was seen with Kt/V urea and serum albumin levels. In conclusion, increased IDWG and UF and elevated BP are independent predictors of LVH for HD patients. Increased volume status leads to IDWG and elevated BP and eventually causes severe LVMI increases.Öğe Parameters of oxidative stress and echocardiographic indexes in patients on dialysis therapy(Taylor & Francis Ltd, 2010) Kayabasi, Hasan; Sit, Dede; Atay, A. Engin; Yilmaz, Zulfukar; Kadiroglu, Ali Kemal; Yilmaz, M. EminAim: Quantity of oxidative stress (OS) is enhanced in every stage of chronic renal failure (CRF). OS and its effects on echocardiographic indexes in patients on hemodialysis (HD) and continuous ambulatory peritoneal dialysis (CAPD) were evaluated. Materials and methods: Thirty-nine patients on CAPD, 32 patients on HD, and 30 healthy individuals with similar demographic features were included. Patients with diabetes mellitus and chronic inflammatory diseases were excluded. Blood samples were collected to examine hematological and biochemical parameters and levels of malonyldialdehyde (MDA), glutathione peroxidase (GSH-px), and superoxide dismutase (SOD) after a 12-hour fasting period in the middle of dialysis week. OS parameters were compared with ejection fraction (EF), interventricular septum diameter (IVSd), left ventricular posterior wall diameter (LVPWd), and left atrium diameter (LAd) determined in M-mod echocardiographic examination. Results: No significant difference was observed between MDA and GSH-px levels of patients and control group; however, SOD levels of patients group were significantly lower (p < 0.0001). SOD levels of patients on HD were lower than that of patients on CAPD (p = 0.039). Negative correlation was detected between MDA and EF (r = -0.380, p = 0.001); SOD has negative correlation with systolic blood pressure (r = -0.265, p = 0.011), diastolic blood pressure (r = -0.230, p = 0.028), phosphorus (r = -0.327, p = 0.001), intact parathyroid hormone (iPTH) (r = -0.259, p = 0.013), C-reactive protein (CRP) (r = -0.235, p = 0.024), fibrinogen (r = -0.342, p = 0.001), and total cholesterol (r = -0.249, p = 0.017); and positive correlation with hemoglobin (r = 0.414, p < 0.001) and albumin (r = 0.367, p < 0.001). MDA was independently related with age (beta = -0.258, p = 0.035), male gender (beta = -0.312, p = 0.004), and EF (beta = -0.461, p < 0.001). No correlation was determined between antioxidants and cardiac indexes. Conclusion: SOD levels decreased significantly especially in patients on HD, and it was observed that lower levels of SOD would lead to OS in patients on HD and CAPD when compared to healthy individuals; MDA levels were independently influenced from EF.Öğe Peritoneal Scintigraphy in Diagnosis of Peritoneal Leakage(Turk Nefroloji Diyaliz Transplantasyon Dergisi, 2008) Kadiroglu, A. Kemal; Kayabasi, Hasan; Altunci, Gulhan; Kaya, Halil; Yilmaz, M. EminAbdominal hernias and peritoneal leakage are mechanic complications of peritoneal dialysis. We want to present a nonobes type 2 diabetic female patient treated with continuous ambulatory peritoneal dialysis ( CAPD) who had left inguinal hernia due to peritoneal leakage detected by peritoneal scintigraphy. A 38-year-old female patient who has been on CAPD programme for 6 years was suffering from a swelling in her left inguinal region and a little decline in ultrafiltration rate in last two week. Fascial structure was intact by abdominopelvic ultrasound and computed tomography. In peritoneal scintigraphy; increased activity attachments were observed at the left inguinal side after first hour. The patient was transferred to the hemodialysis programme three times a week for 1 month temporarily. After 1 month, peritoneal leakage and fluid accumulation were not observed in the control peritoneal scintigraphy. The patient began to CAPD therapy again. In conclusion, peritoneal scintigraphy should be considered in detection of the dialysate leakage in patients on CAPD that failed to be diagnosed by abdominopelvic USG and computed tomography.Öğe Prevalance of ACE Gene Polymorphism in Patients with End Stage Kidney Disease in Southeastern Turkey(Turk Nefroloji Diyaliz Transplantasyon Dergisi, 2007) Zerman, Avar; Sit, Dede; Kadiroglu, Ali Kemal; Kayabasi, Hasan; Budak, Metin; Yilmaz, Zi. Ilflikar; Yilmaz, M. EminAim: To evaluate the frequency of angiotensin converting enzyme gene polymorphism from renin angiotensin aidosterone system in patients undergoing chronic dialysis. Materials and Methods: Eighty-seven patients undergoing di;. alysis treatment and 38 healthy volunteers were enrolled in the study. Demographic features, arterial blood pressure, body mass index (BMI, hematological and biochemical parameters were recorded. ACE gene polymorphism was studied using sterile polymerase chain reaction (PCM method from blood samples taken into tubes containing EDTA. Results: Of the 87 patients, 49 were undergoing hemodialysis and 38 were on peritoneal dialysis programme. In the patient group male/female ratio was 48139 and the mean age was 41.11 +/- 13.6 years; in controls male/female ratio was 14,24 and the mean age was 38.0 +/- 1.41 years. Diabetes mellitus, hypertension, chronic glomerulonephritis were the first three causes of ESRD with percentages of 28, 24, and 23% respectively. Systolic and diastolic blood pressures were higher in patients than controls. ACE gene (I/D) polymorphism prevalence was found as 0.9%, 44.8%, 45.9% among patients. and 31.5%, 39.4%, 28.9% among controls for 11/D/DD respectively, and statistical significance was found (p=0.006). ACE D allele frequency was 68.4% among patients, and 48.7% among controls (p=0.001). Conclusion: We found difference in dispersion of ACE genotype and frequency of D allele between patients and controls.
