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    Antecedents and concomitants of parenting stress in adolescent mothers in foster care
    (Pergamon-Elsevier Science Ltd, 2009) Celik, Yusuf; Celik, Fatma
    [Abstract Not Available]
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    Association between adverse perinatal outcomes and amino acid levels measured with nutrient questionnaire in adolescent pregnancies
    (Lippincott Williams & Wilkins, 2016) Guzel, Ali Irfan; Cinar, Mehmet; Erkilinc, Selcuk; Aksoy, Rifat Taner; Yumusak, Omer Hamid; Celik, Fatma; Celik, Yusuf
    Background: To evaluate the maternal serum amino acid levels in first trimester adolescent pregnancies by using a new developed dietary questionnaire. Methods: A group of 169 pregnant women in the first trimester of their pregnancy were asked to complete the dietary questionnaire. Among all the women, 39 were adolescent pregnancies. The results of the questionnaire were evaluated by a nutrient database program (BeBiS software program) designed to evaluate Turkish traditional foods and commercial processed foods. Results: There was no statistically significant difference between the groups in terms of body mass index and educational and socio-economic status. The mean age and gravidity was statistically significantly lower in adolescent pregnancies. The mean isoleucine, leucine, lysine, methionine, phenylalanine, tyrosine, threonine, valine, arginine, and proline levels were statistically significantly lower in adolescent pregnancies. Receiver operating characteristic (ROC) curve analysis showed the cut-off values of these amino acids. Of these amino acids; lower values of histidine, serine, and alanine were associated with lower birth weight, and lower values of histidine and alanine were associated with preterm delivery. Conclusion: To the best of our knowledge, this is the first study evaluating the amino acid levels in adolescent pregnancies. According to this study, some amino acid levels were lower in adolescent pregnancies and associated with adverse perinatal outcomes. Further studies with maternal and perinatal outcomes are needed to demonstrate the effects of these amino acids in such pregnancies. Copyright (C) 2016, the Chinese Medical Association. Published by Elsevier Taiwan LLC. This is an open access article under the CC BY-NC-ND license.
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    THE ASSOCIATION BETWEEN FEEDING HABITS, NUTRITIONAL PARAMETERS AND QUALITY OF SLEEP IN HEMODIALYSIS PATIENTS
    (Oxford Univ Press, 2013) Kose, Esra; Turgutalp, Kenan; Kiykim, Ahmet; Celik, Fatma; Oguz, Ebru Gok
    [Abstract Not Available]
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    The Association Between Feeding Habits, Nutritional Parameters and Quality of Sleep in Hemodialysis Patients
    (Turk Nefroloji Diyaliz Transplantasyon Dergisi, 2014) Kose, Esra; Turgutalp, Kenan; Kiykim, Ahmet; Celik, Fatma
    OBJECTIVE: Poor sleep and sleep-related breathing disorders are common in hemodialysis (HD) patients. However, it is not well known whether there is a relation between nutritional habit and quality of sleep. The aim of this study was to investigate the relation between quality of sleep and nutritional characteristics. MATERIAL and METHODS: The study population included 84 HD patients. Data were collected with the questionnaire developed by the researchers and included questions about socio-demographic features, biochemical findings, and anthropometric data. RESULTS: The quality of sleep was poor in 51.2% of the patients. These patients were relatively older than the patients with good quality of sleep (44.0 +/- 13.0 and 37.4 +/- 11.8 year respectively, p<0.001). The patients with the good quality of sleep consumed significantly more meat-offal-cheese-egg (p<0.01) and fruit (p<0.05). The patients with the poor quality of sleep had significantly lower albumin (p<0.01), pre-albumin (p=0.02) and total lymphocyte counts (p=0.02). The patients who more frequently had gastrointestinal complaints (especially abdominal discomfort and flatulence) had the poor quality of sleep. CONCLUSION: There are some associations between sleep quality and nutritional aspects. Nutritional habits should be evaluated in HD patients having poor sleep quality.
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    The contribution of nitric oxide on the relaxation effects of diethylstilbestrol
    (Saudi Med J, 2008) Hekimoglu, Askin; Celik, Fatma; Tas, Taskin; Ece, Aydin; Kavak, Vatan
    Objectives: To evaluate the contribution of nitric oxide (NO) on the relaxation effects of diethylstilbestrol on rat uterus. Methods: Uterine rings from 8 nonpregnant Wistar Albino rats (300-350g) in the pro-estrous phase were suspended in an organ bath and electrical field stimulation applied for recording isometric tension. The influence of NO on contractile responses of rat uterine rings was investigated. The effects of NO precursor L-arginine (10(-7)-10(-4)M) concentration and NO synthase inhibitor L-nitro-arginine-methyl ester (10(-7)-10(-4)M) concentration and a combination of them on contractile responses were studied in the presence and absence of diethylstilbestrol (2x10(-4)M) concentration. The study was carried out at the Department of Pharmacology Laboratory, Faculty of Medicine, Dicle University, Diyarbakir, Turkey. Results: Totally, 30 samples were investigated (n=6 for each group, 5 groups). Diethylstilbestrol inhibited contractile responses 64.2 +/- 4.5% (n=6, p<0.05). Contractile responses decreased in the presence of Larginine (n=6, p<0.05) and this inhibition was abolished in the presence of L-nitro-arginine-methyl ester (n=6, p<0.05). The inhibition on contractile responses to diethylstilbestrol was potentiated in the presence of Larginine under similar conditions (n=6, p<0.05). The contractile responses to electrical field stimulation in the presence of diethylstilbestrol were not affected by L-nitro-arginine-methyl ester (n=6, p>0.05). Conclusions: These data provide evidence that NO may potentiate the inhibitory effects of diethylstilbestrol by different mechanisms on the electrically induced contractions of the non-pregnant rat uterus.
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    Dietary antioxidant levels in hyperemesis gravidarum: A case control study
    (Via Medica, 2011) Celik, Fatma; Irfan, Guzel Ali; Kuyumcuoglu, Umur; Celik, Yusuf
    Objectives: Dietary antioxidant intake decreases the risk of many diseases. Hyperemesis gravidarum (HG) is the most common eating disorder during pregnancy Therefore, the authors conducted this prospective and case control study to evaluate dietary antioxidant levels of women with HG and compare with healthy pregnant women. Material and Methods: This prospective case control study was conducted at a government hospital in the southeastern region of Turkey from February 2010 to May 2010. A total of 100 pregnant women were included into the study Dietary antioxidant levels (DAL) were measured according to the new 92-item antioxidant nutrient questionnaire developed by Satia et al (1). 50 women with HG and 50 healthy pregnant women were evaluated. Statistical analyses were carried out with statistical packages for SPSS 15.0 for Windows (SPSS Inc., Chicago, IL, USA). Results: There were no statistically significant differences between the groups regarding the age of the patients, gestational age, educational status, body height and weight (p >.05). Vitamin E, E equivalent, vitamin C, carotene and vitamin A levels were significantly lower in women with HG (p <.05). The results of logistic regression method for these variables including odds ratio (95 % CI) were as follows: 10.07(1.52-66.51), 7.37(2.66-20.41), 4.26(2.66-20.41), 3.66(2.38-5.63) and 2.75 (1.56-4.85), respectively Conclusion: According to this study vitamin E, E equivalent, vitamin C, carotene and vitamin A levels of women may play a role in the pathogenesis of HG. Therefore, diet recommendations should be given by clinicians before pregnancy
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    Nutritional risk factors for the development of chronic obstructive pulmonary disease (COPD) in male smokers
    (Churchill Livingstone, 2006) Celik, Fatma; Topcu, Fusun
    Background & Aims: The aim of this study was to investigate whether nutritional risk factors, especially black tea consumptions, are inversely associated with the development of chronic obstructive pulmonary disease (COPD) in male smokers. Methods: Forty male smokers with clinical diagnosis of COPD (Group-I (GI)) and 36 healthy smokers without COPD (Group-II (GII)) were included in this study. We compared the dietary habits and food intakes of the two groups using an adaptation of the Arizona Food Frequency Questionnaire (AFFQ). Question form included a list of 65 food items formed from five main food groups (grain, meat and alternatives, dairy products, vegetables-fruits and fat) and 25 dietary habits. The data were evaluated by binary logistic regression analysis, receiver operating characteristic (ROC) curve, Kolmogorov-Smirnov, Student's t, Mann-Whitney, and Chi-square tests. Results: When both groups compared, black tea consumptions (GI-700 ml; GII-1600ml (OR: 0.635, P < 0.001)), vegetable fruits scores (GI-54.30; GII-63.81 (OR: 0.863, P < 0.001)), regularly breakfast habit (GI-24 patients; GII-36 cases (OR: 0.549, P < 0.001)) and eating salty (GI-22 patients; GII-5 cases (P < 0.001)) made significant differences. In ROC curves, the area under the curve of black tea (0.898 (95% CI: 0.819-0.977) and vegetables-fruits (0.833 (95% CI: 0.727-0.938) provided high accuracy to distinguish between COPD group and controls (P < 0.001). Conclusions: High intakes of black tea and vegetables-fruits consumptions may be protecting male smokers from developing COPD. (c) 2006 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.
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    Nutritional risk factors for the development of hypertension in diabetic patients
    (Elsevier Science Inc, 2009) Celik, Fatma; Celik, Murat; Akpolat, Veysi
    The aim of this cross-sectional study was to determine the significant limitations, sensitivity, specificity, partial correlations, and odds ratios of nutrient intake in patients with and without hypertension with Type 2 diabetes mellitus. Diabetic patients (n=220) with clinical diagnosis of hypertension and diabetic patients (n=230) without hypertension were included in this study. The questionnaire form included a list of 65 food items formed from five main food groups (grain, meat and alternatives, dairy products, vegetables-fruits and fat) and 25 dietary habits. When both groups were compared and analyzed by logistic regression, black tea consumption (OR=0.823, P<.001), vegetables-fruits scores (OR=0.853, P<.001), triglycerides (OR=0.726, P<.05), waist-to-hip ratio (WHR) (OR=0.777, P<.01) and high-density lipoprotein cholesterol (HDL-C) (OR=0.526, P<.001) made significant differences. In ROC curves, the area under the curve of black tea (0.921), vegetables-fruits (0.906), triglycerides (0.889), WHR (0.881) and HDL-C (0.820) provided high accuracy to distinguish between patients with and without hypertension (P<.001). In diabetic patients without hypertension, significant partial correlations were observed between blood pressure and dairy products (systolic: r=)0.14; diastolic: r=)0.14, P<.05), vegetables-fruits groups (systolic: r=)0.18; diastolic: r=)0.17, P<.01) and black tea intake (systolic: r=)0.23; diastolic: r=)0.22, P<.001). It has been found that higher intake of black tea and vegetables-fruits consumption in diabetic patients protect against developing hypertension. (C) 2009 Published by Elsevier Inc.
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    Paraoxonase, total antioxidant activity and peroxide levels in marasmic children
    (Pergamon-Elsevier Science Ltd, 2007) Ece, Aydın; Gurkan, Fuat; Celik, Fatma; Boşnak, Mehmet; Yel, Servet; Balik, Hasan; Erel, Ozcan
    Objectives: The aim of this study was to investigate the oxidant/antioxidant status, paraoxonase (PON) activity and leptin. levels in children with marasmic malnutrition. Design and methods: Thirty marasmic children (age 14.4 +/- 10.3. months) and 28 control subjects were included; Plasma PON activity, total antioxidant activity (TAO), total peroxide (TPX) and leptin,levels were measured. Results: Malnourished children had significantly. lower leptin.(3.6 +/- 1.1. vs. 11.8 +/- 4.5 ng/mL, P < 0.001), PON. activity (66.4 +/- 28.6 vs. 2213 +/- 31.6 IU/L, P < 0.001) and. TAO (1.44 +/- 0.12 vs. 2.45 +/- 0.61 mmol Trolox equiv/L, P < 0.001); and higher TPX (15.6 +/- 6.4 vs. 5.9 +/- 1.9 mu mol/L, P < 0.001) values than,in controls. Significant negative correlation was found between PON and TPX (P=0.040) and positive correlation between TAO and BMI (P= 0.034) in patients. No significant correlation was found between leptin and oxidam/antioxidant parameters (P > 0.05). Conclusions: Children with marasmic. malnutrition had increased. pro-oxidant and decreased antioxidant status. Extent of oxidative stress increases with malnutrition severity.. Antioxidants could be given during nutritional rehabilitation., (c) 2007 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.
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    Postprandial hyperlipidemia in overt and subclinical hypothyroidism
    (Elsevier Science Bv, 2012) Arikan, Senay; Bahceci, Mithat; Tuzcu, Alpaslan; Celik, Fatma; Gokalp, Deniz
    Background and aims: Lipid alterations in overt hypothyroidsm (OH) were well known, but its changes in subclinical hypothyroidism (SCH) and postprandial period were not clear. The aim of this study is to evaluate postprandial lipemia by oral lipid tolerance test (OLTT) in patients with OH and SCH. Materials and methodology: Twenty-five OH and 27 SCH, totally 52 hypothyroid patients [mean age 38.3 +/- 12.8 year, body mass index (BMI): 29.0 +/- 5.8 kg/m(2)] and 23 BMI- and age-matched healthy controls (mean age 36.7 +/- 11.9 years; BMI: 27.1 +/- 6.9 kg/m(2)) were included to the study. Anthropometric measurements and HOMA-IR levels were measured. Basal and postprandial lipid profile at 2nd, 4th, 6th and 8th hours were determined by oral lipid tolerance test. Results: There were not any statistical differences among three groups (control, OH and SCH) in terms of mean fasting levels of total cholesterol, LDL-cholesterol, VLDL-cholesterol, and triglyceride. On the contrary, mean triglyceride levels at postprandial 8th hour in both OH and SCH patients were higher than control subjects (p=0.017 and p=0.049, respectively). Again mean postprandial 8th hour VLDL-cholesterol levels in OH group were also higher than control subjects (p=0.05). In addition mean HOMA-IR value of SCH and OH patients was similar with control subjects (1.5 +/- 1.4 in OH; 1.3 +/- 0.8 in SCH; 2.2 +/- 2.2 in control group). Conclusions: Although total, LDL and VLDL-cholesterol, and triglyceride levels were not different from healthy controls, triglyceride and/or VLDL-cholesterol levels apparently increased with OLTT in both OH and SCH patients. Decreased lipid clearance may be responsible for this result. (c) 2012 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.
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    Serum citrulline levels in infants with short bowel syndrome
    (Mosby-Elsevier, 2006) Celik, Yusuf; Celik, Fatma
    [Abstract Not Available]