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Öğe Color doppler imaging of ocular hemodynamic changes in Behcet's disease(Elsevier Science Inc, 2004) Çaça, I; Nazaroglu, H; Ünlü, K; Cakmak, SS; Ari, S; Sakalar, YBPurpose: A prospective evaluation of the Ocular blood flow velocity in patients with Behcet's disease was carried out to determine its changes. Methods: Subjects were divided into three groups: those with ocular involvement in Behcet's disease (goup I), those without ocular involvement in Behcet's disease (goup II), and a control group (group III). Twenty-seven eyes in group I and 28 eyes each in groups II and III were investigated. The blood flow in the central retinal artery (CRA), ophthalmic artery (OA), nasal posterior ciliary artery (NPCA), and the temporal posterior ciliary artery (TPCA) was measured using color Doppler ultrasonography (CDU) to determine the peak systolic velocity (PSV), end diastolic velocity (EDV), and resistivity index (RI). The mean blood flow velocity of the central retinal vein (CRV) was also measured. These results were then compared among the three groups of subjects. Results: The PSV values of CRA in groups I and II were found to he significantly lower than those in the control group (P < 0.001, P = 0.018, respectively). The PSV values of CRA in group I were found to be significantly lower than those in group II (P < 0.001). The EDV values of CRA in groups I and II were found to be significantly lower than those in the control group (P < 0.001, P = 0.034, respectively). The EDV values of CRA in group I were significantly lower than those in group II (P = 0.041).The PSV values of OA in group I were significantly lower than those in the control group (P = 0.002). The EDV values of OA in group I were significantly lower than those values in group II or the control group (P = 0.001 and P = 0.037. respectively).The PSV values of NPCA in group I were significantly lower than those ill the control group (P = 0.007). The PSV Values of TPCA in groups I and II were significantly lower than those ill the control group (P < 0.001. P < 0.001. respectively). The EDV values of TPCA in group I were significantly lower than those values in group II or the control group (P = 0.014 and P = 0.003, respectively). There were no significant differences in the mean blood flow values of the CRV among all three groups (P > 0.05). Conclusions: There are significant reductions in the blood flow values of the orbital arteries in patients with Behcet's disease, and they are more evident in those with ocular involvement. This might be the result of occlusive vasculitis, which is frequently seen in the retinal vessels of patients with Behcet's disease. (C) Japanese Ophthalmological Society 2004.Öğe Conjunctival deposits as the first sign of systemic sarcoidosis in a pediatric patient(Wichtig Editore, 2006) Çaça, I; Ünlü, K; Büyükbayram, H; Ari, SPURPOSE. Sarcoidosis is an inflammatory disease of unknown cause, characterized by noncaseating, granulomas. In this study, the authors present a sarcoidosis patient without systemic signs diagnosed by histopathologic analysis of conjunctival deposits. METHODS. A 10-year-old girl had bilateral, focal, multilobular, multiple pale yellow deposits in bulbar conjunctiva for a year. In the patient's biomicroscopic examination, numerous 0.50 to 2-mm diameter pale yellow deposits were determined in both bulbar conjunctivas. The patient had no other systemic or ocular complaints. A conjunctival biopsy was performed. RESULTS. The biopsy specimens showed noncaseating granulomas with prominent asteroid bodies. Serum angiotensin-converting enzyme levels were increased in the patient. Conjunctival deposits were the first manifestation of sarcoidosis in the patient and the diagnosis of sarcoidosis was confirmed with a conjunctival biopsy. CONCLUSIONS. To the authors' knowledge, this is the second study that reports a sarcoidosis patient with non-systemic involvement diagnosed after histopathologic analysis of conjunctival deposits.Öğe Cutaneous anthrax on eyelids(Elsevier Science Inc, 2004) Çaça, I; Çakmak, SS; Ünlü, K; Sakalar, YB; Kadiroglu, AKBackground: Ophthalmologists should be aware of the signs and symptoms of anthrax, although it is a rare disease in humans. We report our successful treatment of three patients with cutaneous lesions in the periorbital area. Cases: In this study, we report on the treatment of three female patients who were initially diagnosed as having preseptal cellulitis. Observations: Gram-positive robs were revealed in the microscopic examination of scrapings taken from the lesions. Bacillus anthracis was found in only two of the three scraping-material cultures. Intravenous penicillin G was administered in all cases. Black and necrotic eschar, which is characteristic of anthrax, developed on the eyelids of all three patients during treatment. At the final examinations of the patients after the completion of treatment, we recognized the development of cicatrisation, lagophthalmos, and slight ectropion in the upper eyelid of the first patient, and, in the second patient, restriction of upper eyelid movement and development of a corneal scar from exposure keratopathy and ectropion. The cutaneous lesions healed without any eyelid pathology in the third patient. Conclusion: Although it is a rare disease in humans, anthrax should be considered in the differential diagnosis of preseptal and orbital cellulitis. (C) Japanese Ophthalmological Society 2004.Öğe External ophthalmomyiasis infestation(Elsevier Science Inc, 2006) Çaça, I; Satar, A; Ünlu, K; Sakalar, YB; Ari, S[Abstract Not Available]Öğe Orbital myiasis(Elsevier Science Inc, 2003) Çaça, I; Ünlü, K; Çakmak, SS; Bilek, K; Yildirim; Sakalar, B; Ünlü, GBackground: Orbital myiasis cases are very rare worldwide. We are reporting this case caused by Hypoderma bovis because invasive parasitic larvae can cause massive destruction. Case: An 85-year-old female patient was admitted to the Department of Ophthalmology of the Dicle University School of Medicine with the complaint of a wound in her right eye for over one year. Larvae had been in the same eye for one week. Observations: The clinical examination showed no light perception in her right eye. The eyelid was thickened and there was a necrotic lesion 3 x 4 cm in diameter, invading inferiorly into the upper side of the maxilla, superiorly to the roof of the orbita, medially to the lateral part of the nose, and laterally to the ossa zygomatica. Pathological examination of orbital tissue specimens confirmed basal cell carcinoma. Conclusions: Orbital exenteration, total maxillectomy and graft repair were conducted in the right eye. During the six-month follow-up period, orbital tomography was performed. No recurrence or metastasis was observed. (C) 2003 Japanese Ophthalmological Society.Öğe Spontaneous fracture of an implanted posterior chamber intraocular lens(Sage Publications Ltd, 2005) Çaça, I; Ünlü, K; Ari, S; Aksit, IPURPOSE. Spontaneous fracture of an intraocular lens (IOL) haptic is a rare complication of cataract surgery. The authors report a case of spontaneous fracture of an implanted posterior chamber IOL. CASE. CASE. Five years ago, a 12-year-old patient underwent linear lens extraction, posterior capsulotomy, and anterior vitrectomy due to traumatic cataract and received a polymethyl methacrylate (PMMA) biconvex posterior chamber IOL implanted in ciliary sulcus. Five years later, IOL optic was found in anterior chamber with its haptics broken from the optic-haptic junction. DISCUSSION. The broken haptic was examined with scanning electron microscopy. The fracture site of the haptic was on the optic-haptic junction. The fractured surface had a regular appearance. DISCUSSION. The broken haptic was examined with scanning electron microscopy. The fracture site of the haptic was on the optic-haptic junction. The fractured surface had a regular appearance. CONCLUSIONS. To our knowledge, this is the fourth report of spontaneous fracture of an implanted posterior chamber IOL.Öğe Therapeutic effect of culture and antibiogram in bacterial corneal ulcers(Amer Soc Contemporary Ophthalmology, 2005) Çaça, I; Ünlü, K; Ari, S; Sakalar, YBCorneal scraping material was taken from 58 eyes of 58 patients with bacterial corneal ulcer. Ulcer size and epithelial healing were determined using biomicroscopy. A combination of cefazolin 33 mg/mL and gentamycin 14 mg/mL was administered before cultures results were returned. Mean ulcer size and epithelial healing in culture negative patients were significantly lower than in culture positive patients.Öğe Unilateral optic disc edema in a patient with acute lymphocytic leukemia -: A case and review of the literature(Amer Soc Contemporary Ophthalmology, 2005) Çaça, I; Ünlü, K; Ari, S; Dirier, AA young male complained of acute left-eye visual loss. The right eye was normal. Only hand motions were seen with the left. The dilated fundus showed mild optic disk elevation, blurred margins, tortuous vessels, retinal vascular sheathing, and flame-shaped hemorrhages. Laboratory exam revealed acute lymphocytic leukemia. Following chemotherapy and radiotherapy, disk swelling and retinal changes resolved and visual acuity improved.
