Therapeutic effect of culture and antibiogram in bacterial corneal ulcers

Corneal scraping material was taken from 58 eyes of 58 patients with bacterial corneal ulcer. Ulcer size and epithelial healing were determined using biomicroscopy. A combination of cefazolin 33 mg/mL and gentamycin 14 mg/mL was administered before cultures results were returned. Mean ulcer size and epithelial healing in culture negative patients were significantly lower than in culture positive patients.