Evaluation of specific heavy metal levels of pregnant women complicated by neural tube defects

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dc.authorid0000-0003-1349-1569en_US
dc.authorid0000-0001-7616-4181en_US
dc.authorid0000-0001-5463-4197en_US
dc.authorid0000-0001-5695-2586en_US
dc.authorid0000-0002-8100-0242en_US
dc.authorid0000-0002-3285-9990en_US
dc.contributor.authorKaraçor, Talip
dc.contributor.authorKırıcı, Pınar
dc.contributor.authorNacar, Mehmet Can
dc.contributor.authorBülbül, Mehmet
dc.contributor.authorÖnderci, Muhittin
dc.contributor.authorPeker, Nurullah
dc.date.accessioned2023-10-20T11:34:05Z
dc.date.available2023-10-20T11:34:05Z
dc.date.issued2020en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kadın Hastalıkları ve Doğum Ana Bilim Dalıen_US
dc.description.abstractAim: The etiology of neural tube defect (NTD) is still not clear enough. In our study, we aimed to evaluate plasma heavy metal levels of pregnant women with NTD and to determine whether there is a relationship between heavy metal levels and NTD severity. Material and Methods: TThis study was conducted in Adıyaman University, Department of Gynaecology and Obstetrics. The study included 38 pregnant women with NTD and 42 pregnant women with healthy infants. Pregnant women who have NTD were divided into two groups as NTD Type 1 and NTD Type 2 according to the anomaly type. Levels of heavy metals such as Mercury (Hg), Cadmium (Cd), Cobalt (Co), Lead (Pb), Manganese (Mn) and Arsenic (As) were compared between groups. Results: Plasma Hg, Co, Cd and Pb levels were higher in NTD group than control group. (p values, respectively; p <0.001, p = 0.001, p <0.001, p <0.001). As and Mn levels were not statistically different between the two groups (p values; p = .519, p = .819, respectively). In the NTD group, Hg was found to be higher in NTD Type 1 than NTD Type 2 (p <0.001). Conclusion: It is obvious that some histomorphological changes are formed in the cardinal ligaments of patients with uterine prolapse due to pressure on the uterus. We believe that the increase in the number of extravasated erythrocytes and the thickness of the vascular wall and peripheral nerve should be supported by further studies.en_US
dc.identifier.citationKaraçor, T., Kırıcı, P., Nacar, M. C., Bülbül, M., Önderci, M. ve Peker, N. (2020). Evaluation of specific heavy metal levels of pregnant women complicated by neural tube defects. Annals of Medical Research, 27(2), 454-460.en_US
dc.identifier.doi10.5455/annalsmedres.2019.12.889
dc.identifier.endpage460en_US
dc.identifier.issn2636-7688
dc.identifier.issue2en_US
dc.identifier.startpage454en_US
dc.identifier.trdizinid364503
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/364503
dc.identifier.urihttps://hdl.handle.net/11468/12898
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/364503
dc.identifier.volume27en_US
dc.indekslendigikaynakTR-Dizin
dc.institutionauthorPeker, Nurullah
dc.language.isoenen_US
dc.publisherİnönü Üniversitesi Tıp Fakültesien_US
dc.relation.ispartofAnnals of Medical Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAnencephalyen_US
dc.subjectHeavy metalen_US
dc.subjectNeural tube defecten_US
dc.subjectPregnancyen_US
dc.subjectSpina bifidaen_US
dc.titleEvaluation of specific heavy metal levels of pregnant women complicated by neural tube defectsen_US
dc.titleEvaluation of specific heavy metal levels of pregnant women complicated by neural tube defects
dc.typeArticleen_US

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