Immunohistochemical localisation of oestrogen and epidermal growth factor receptors of the bitch uterus in the sexual cycle

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dc.contributor.authorOzyurtlu N.
dc.contributor.authorSagsoz H.
dc.contributor.authorSaruhan B.G.
dc.contributor.authorZonturlu A.K.
dc.contributor.authorKetani M.A.
dc.contributor.authorAkbalik M.E.
dc.date.accessioned2024-04-24T18:44:15Z
dc.date.available2024-04-24T18:44:15Z
dc.date.issued2010
dc.departmentDicle Üniversitesien_US
dc.description.abstractThe localisation of oestrogen (ER) and epidermal growth factor receptors (EGFR) in the various cell types of the bitch uterine was determined. In this study, 23 adult, healthy crossbred bitches brought to the clinic for ovariohisterectomy were used. ER and EGFR positive staining was detected in all cell types of the uterus. A distinct staining was seen in the luminal and glandular epithelium; while stromal and myometrial cells showed weak or moderate staining. The endothelial and smooth muscle cells of the vessels in the endometrium and myometrium sometimes appeared positive. No staining was observed in the mesothelium. The results of this study suggested that ER and EGFR were expressed at various levels in different cell types of bitch uterus. In light of the previous studies, and data of the presented investigations, it may be necesssary to elicit the harmonious proliferation and differentiation of epithelial and stromal cells that are considered essential for the preparation of the uterus for implantation.en_US
dc.identifier.endpage200en_US
dc.identifier.issn0042-4870
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-77954579545
dc.identifier.scopusqualityN/A
dc.identifier.startpage193en_US
dc.identifier.urihttps://hdl.handle.net/11468/24623
dc.identifier.volume54en_US
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.relation.ispartofBulletin of the Veterinary Institute in Pulawy
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBitchen_US
dc.subjectEpidermal Growth Factoren_US
dc.subjectImmunohistochemistryen_US
dc.subjectOestrogenen_US
dc.subjectReceptorsen_US
dc.subjectUterusen_US
dc.titleImmunohistochemical localisation of oestrogen and epidermal growth factor receptors of the bitch uterus in the sexual cycleen_US
dc.titleImmunohistochemical localisation of oestrogen and epidermal growth factor receptors of the bitch uterus in the sexual cycle
dc.typeArticleen_US

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