Genipin Cross-linked Boron Doped Hydrogels: Evaluation of Biological Activities

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dc.contributor.authorBursali, Elif Ant
dc.contributor.authorAbaci, Diler
dc.contributor.authorKizil, Murat
dc.contributor.authorYurdakoc, Muruvvet
dc.date.accessioned2024-04-24T17:20:44Z
dc.date.available2024-04-24T17:20:44Z
dc.date.issued2021
dc.departmentDicle Üniversitesien_US
dc.description.abstractGenipin cross-linked/boron doped starch/polyvinily alcohol (PVA) based hydrogel (SH-GNP-B) was synthesized as a new material having antimicrobial and antioxidant activity. The prepared hydrogel was characterized by X-ray Diffraction (XRD), Fourier Transform Infrared Spectroscopy (FTIR), Thermal Gravimetric Analysis (TGA) and Scanning Electron Microscope (SEM) methods and evaluated for in vitro antimicrobial activities against selected organisms by disc diffusion tests.The antioxidant activity of the prepared hydrogels was evaluated using 2,2-diphenyl-1-picrylhydrazyl radical scavenging assays. Swelling behavior of the hydrogel was also investigated. The synthesized hydrogel was thermally stable and showed pH independent swelling tendency. SH-GNP-B hydrogel was found to have antimicrobial activities against Staphylococcus aureus, Streptecocus pyogenes, Pseudomonas aeruginosa and Bacillus subtilis microorganisms and antioxidant activities. The antimicrobial activity was improved more effectively by doping boric acid (B) to hydrogel. The hydrogel exhibited weak antioxidant activity when compared to butylated hydroxytoluene (BHT).en_US
dc.description.sponsorshipScientific and Technological Research Council of Turkey (TUBITAK) [2209-A]; University Students Research Projects Support Program; DPPH radical scavenging activities of hydrogelsen_US
dc.description.sponsorshipFinancial support for this research was provided by the Scientific and Technological Research Council of Turkey (TUBITAK) Project Number 2209-A, University Students Research Projects Support Program. We would like to thank to Nesrinnceren and Feryal Akay for determining the DPPH radical scavenging activities of hydrogels.en_US
dc.identifier.doi10.32381/JPM.2021.38.3-4.5
dc.identifier.endpage245en_US
dc.identifier.issn0973-8622
dc.identifier.issue3-4en_US
dc.identifier.startpage231en_US
dc.identifier.urihttps://doi.org/10.32381/JPM.2021.38.3-4.5
dc.identifier.urihttps://hdl.handle.net/11468/19221
dc.identifier.volume38en_US
dc.identifier.wosWOS:000877821200005
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.language.isoenen_US
dc.publisherPrints Publications Pvt Ltden_US
dc.relation.ispartofJournal of Polymer Materials
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGenipinen_US
dc.subjectCross-Linkingen_US
dc.subjectAntimicrobial Activityen_US
dc.subjectAntioxidant Activityen_US
dc.subjectHydrogelen_US
dc.titleGenipin Cross-linked Boron Doped Hydrogels: Evaluation of Biological Activitiesen_US
dc.titleGenipin Cross-linked Boron Doped Hydrogels: Evaluation of Biological Activities
dc.typeArticleen_US

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