Non-invasive parameters in the assessment of liver fibrosis.

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dc.contributor.authorDayan, Saim
dc.contributor.authorDal, Tuba
dc.contributor.authorTekin, Recep
dc.contributor.authorDeveci, Ozcan
dc.contributor.authorIpek, Davut
dc.contributor.authorOzcan, Nida
dc.contributor.authorBozkurt, Fatma
dc.date.accessioned2024-04-24T17:47:57Z
dc.date.available2024-04-24T17:47:57Z
dc.date.issued2017
dc.departmentDicle Üniversitesien_US
dc.description.abstractLiver biopsy and histopathological evaluation are the main methods to assess liver pathology. However, liver biopsy is not widely used due to implementation challenge. We aimed to investigate non-invasive parameters for evaluation of liver fibrosis in chronic Hepatitis B patients. A total of 65 patients who admitted to outpatient clinic and diagnosed as chronic hepatitis were included in this study. Liver puncture biopsy was performed for all patients and was evaluated according to the Modified Ishak Fibrosis Score. The patients without fibrosis or with mild and moderate fibrosis were evaluated as Group I (Stage O, I, II), the patients with advanced fibrosis were evaluated as Group II (stage III, IV, V, VI). Among 65 patients, 42 were male and 23 were female; 48 of the patients were in group I while 17 patients belonged to group II. Gamma-Glutamyl Transferase (GGT), Alkaline Phosphatase (ALP), Aspartat Transaminaz (AST) and Alanin Aminotransferaz (ALT) levels were significantly higher in Group II patients. In the assessment of liver fibrosis, liver biopsy remains the gold standard diagnostic method but AST, ALT, GGT, ALP parameters have contribution to this evaluation. Non-invasive testing may be useful in cases which biopsy cannot be performed or repeat biopsy required.en_US
dc.identifier.endpage2184en_US
dc.identifier.issn0970-938X
dc.identifier.issn0976-1683
dc.identifier.issue5en_US
dc.identifier.startpage2180en_US
dc.identifier.urihttps://hdl.handle.net/11468/22825
dc.identifier.volume28en_US
dc.identifier.wosWOS:000396838200048
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.language.isoenen_US
dc.publisherAllied Acaden_US
dc.relation.ispartofBiomedical Research-India
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectLiver Fibrosisen_US
dc.subjectHepatitis Ben_US
dc.subjectAspartat Transaminaz (Ast)en_US
dc.subjectAlanin Aminotransferaz (Alt)en_US
dc.subjectNon-Invasive Parametersen_US
dc.titleNon-invasive parameters in the assessment of liver fibrosis.en_US
dc.titleNon-invasive parameters in the assessment of liver fibrosis.
dc.typeArticleen_US

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