Histological changes in the gingrval tissues of rats subjected to surgical extraction of the adrenal glands

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dc.contributor.authorDag A.
dc.contributor.authorKetani M.A.
dc.contributor.authorZengingul A.I.
dc.contributor.authorUysal E.
dc.contributor.authorBaskan Z.
dc.date.accessioned2024-04-24T18:44:26Z
dc.date.available2024-04-24T18:44:26Z
dc.date.issued2009
dc.departmentDicle Üniversitesien_US
dc.description.abstractHormones are specific regulatory molecules that have potent effects on the major determinants of the development and the integrity of the skeleton and oral cavity also including periodontal tissues. The aim of this study, is to investigate the effect of adrenalectomy on rat gingival tissue. Twenty-eight mature Wistar albino female and male rats divided randomly into 2 groups and in one group adrenalectomy was performed. After 21 days recovery period, Control and Experimental groups were sacrificed under Ketamin HCi anesthesia and clinical and histological observations were made. Microscopic findings, revealed significant changes in adrenalectomized rats. Hypertrophy and thickness of gingival epitelium was apparent in the gingival epithelium of ADX group. Increase in mitotic activity in stratum basale layer of gingival epitelium and increase in keratinisaton layer were observed in adrenalectomized rats. A decrease in collagen fibrils and irregularity of papilla was seen in adrenalectomized rats. Our findings demonstrate the importance of adrenal glands in the development of gingival tissue and suggest that adrenal glands deficiency is one mechanism, by which gingival disorder susceptibility may be increased. © Medwell Journals, 2009.en_US
dc.identifier.endpage547en_US
dc.identifier.issn1680-5593
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-67650476549
dc.identifier.scopusqualityN/A
dc.identifier.startpage545en_US
dc.identifier.urihttps://hdl.handle.net/11468/24697
dc.identifier.volume8en_US
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.relation.ispartofJournal of Animal and Veterinary Advances
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAdrenalectomyen_US
dc.subjectGingival Tissueen_US
dc.subjectHistological Changesen_US
dc.subjectKidney And Hypophysisen_US
dc.subjectRaten_US
dc.subjectWeight Of Liveren_US
dc.titleHistological changes in the gingrval tissues of rats subjected to surgical extraction of the adrenal glandsen_US
dc.titleHistological changes in the gingrval tissues of rats subjected to surgical extraction of the adrenal glands
dc.typeArticleen_US

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