Antimicrobial activity of phytic acid, citric acid, and EDTA with and without propolis against Enterococcus Faecalis and Candida Albicans

dc.contributor.authorÖzata, Merve Yeniçeri
dc.contributor.authorAcer, Ömer
dc.contributor.authorDemirci, Özlem
dc.contributor.authorÇolak, Mehmet
dc.contributor.authorTartuk, Gizem Akın
dc.date.accessioned2024-04-24T17:58:12Z
dc.date.available2024-04-24T17:58:12Z
dc.date.issued2022
dc.departmentDicle Üniversitesi, Diş Hekimliği Fakültesi, Klinik Bilimler Bölümü, Endodonti Ana Bilim Dalıen_US
dc.description.abstractIntroduction: This study aimed to investigate the antimicrobial efficacy of chelation agents on Enterococcus faecalis (E. faecalis) and Candida albicans (C. albicans) when used alone or in combination with propolis. Methods: One hundred fifty mandibular premolar teeth were selected. Each canal was prepared with Reciproc R25. The roots were then divided into two parts along their long axis (n=300). For E. faecalis and C. albicans, the samples were divided into 16 groups (14 experimental and 2 control) as follows: Group 1A-1B [17% Ethylenediaminetetraacetic acid (EDTA)], Group 2A-2B [10% Citric Acid (CA)], Group 3A-3B [1% phytic acid/inositol hexaphosphate (IP6)], Group 4A-4B (17% EDTA+8 mg/mL propolis), Group 5A-5B (10% CA+8 mg/mL propolis), Group 6A-6B (1% IP6+8mg/mL propolis), Group 7A-7B (8 mg/mL propolis), Control A-B (Dimethyl Sulfoxide). Each tooth was randomly irrigated with 2 mL of one of the group solutions or dispersions for 5 min, and the solutions were examined for the bactericidal effect. Results: For C. albicans, all groups showed less optical density (OD) than the control group (P<0.05). The propolis group and the IP6 group had higher OD values than the CA group (P<0.05). For E. faecalis, on the other hand, significantly lower OD values were observed in the propolis+ CA group, compared to the CA and propolis groups (P<0.05). There was no significant difference between microbial growth among IP6, EDTA, propolis+ CA, propolis+IP6, and propolis+ EDTA groups (P>0.05). Conclusion: CA and IP6 showed promising results in eliminating E. faecalis, one of the collective organisms responsible for failed root canals.en_US
dc.identifier.citationÖzata, M. Y., Acer, Ö., Demirci, Ö., Çolak, M. ve Tartuk, G. A. (2022). Antimicrobial activity of phytic acid, citric acid, and EDTA with and without propolis against Enterococcus Faecalis and Candida Albicans. Journal of Dental Materials and Techniques, 11(3), 192-200.
dc.identifier.doi10.22038/JDMT.2022.65976.1522
dc.identifier.endpage200en_US
dc.identifier.issn2322-4150
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85186488567
dc.identifier.scopusqualityQ4
dc.identifier.startpage192en_US
dc.identifier.urihttps://doi.org/10.22038/JDMT.2022.65976.1522
dc.identifier.urihttps://hdl.handle.net/11468/23702
dc.identifier.volume11en_US
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherMashhad University of Medical Sciencesen_US
dc.relation.ispartofJournal of Dental Materials and Techniques
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAntimicrobial efficacyen_US
dc.subjectCitric aciden_US
dc.subjectEdtaen_US
dc.subjectEndodontic microbiologyen_US
dc.subjectPhytic aciden_US
dc.titleAntimicrobial activity of phytic acid, citric acid, and EDTA with and without propolis against Enterococcus Faecalis and Candida Albicansen_US
dc.titleAntimicrobial activity of phytic acid, citric acid, and EDTA with and without propolis against Enterococcus Faecalis and Candida Albicans
dc.typeArticleen_US

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