Electrolyte Imbalance and Its Effect on QTc Interval in PatientsHospitalized with COVID-19

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dc.contributor.authorKanbal, Neşe
dc.contributor.authorÇap, Murat
dc.contributor.authorİnci, Ümit
dc.contributor.authorAltındağ, Rojhat
dc.contributor.authorAkyüz, Abdurrahman
dc.contributor.authorAdıyaman, Mehmet Şahin
dc.contributor.authorBaysal, Erkan
dc.date.accessioned2024-04-24T19:11:56Z
dc.date.available2024-04-24T19:11:56Z
dc.date.issued2020
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjective: Studies have shown that electrolyte abnormalities can be seen in Coronavirus disease 2019 (COVID-19) patients and are associated with the severity of the disease. We aimed to investigate the electrolyte imbalance such as hypocalcemia and hypokalemia in patients hospitalized with COVID-19 and its effect on the QTc interval.Materials and Methods: 185 hospitalized patients with COVID-19 whose diagnosis was confirmed by a real-time reverse transcriptasepolymerase chain reaction and/or Computed Tomography of the chest were included in the study. The potassium and calcium measurements on the admission and third day of hospitalization were recorded. The QTc interval measurement was performed on the admission (QTc-B) and the 3rd-day (QTc-AT) electrocardiography.Results: The median age was 43 (31-56 IQR) and 102 (55.1%) of patients were male. Median baseline potassium level was 4.0 mEq/L (3.7-4.3 IQR) and corrected calcium level was 8.48 mg/dl (8.24-8.73 IQR), whereas the 3rd-day median potassium level was 4.2 mEq/L (3.9-4.5 IQR) and corrected calcium level was 8.42 mg/dl (8.16-8.70 IQR).The median QTc-B interval was found as 427 ms (409-447 IQR) whereas the median QTc-AT interval was found as 438 ms (414-459 IQR). Median 9 ms (-5- 28 IQR) prolongation was observed in the QTc interval, which was statistically significant (p <0.001). There was a significant relationship between QTc-AT and baseline potassium level, potassium level on the 3rd day (respectively ? coefficient= -2.083, 95% CI -27.134- -0.577, p value= 0.041, ? coefficient= -2.547, 95% CI -27.925 - -3.385, p value= 0,013 ) but there was no significant relationship with baseline and 3rd day calcium level. (respectively ? coefficient= -0.848, 95% CI -22.102- 8.919, p value= 0.399, ? coefficient= 0.707, 95% CI -8.685 - 20.784, p value= 0.415)Conclusion: Electrolyte disorders such as hypocalcemia and hypokalemia can be seen in patients hospitalized with COVID-19. After treatment, a significant prolongation was observed in the QTc interval and a significant relationship was observed between QTc-AT and potassium levels, but no significant relationship with calcium was observed.en_US
dc.identifier.endpage9en_US
dc.identifier.issn2147-9488
dc.identifier.issue4en_US
dc.identifier.startpage1en_US
dc.identifier.trdizinid422044
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/422044
dc.identifier.urihttps://hdl.handle.net/11468/28258
dc.identifier.volume51en_US
dc.indekslendigikaynakTR-Dizin
dc.language.isoenen_US
dc.relation.ispartofActa Medica
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleElectrolyte Imbalance and Its Effect on QTc Interval in PatientsHospitalized with COVID-19en_US
dc.titleElectrolyte Imbalance and Its Effect on QTc Interval in PatientsHospitalized with COVID-19
dc.typeArticleen_US

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