Rare Breast Cancer Types: A Study About Characteristics, Outcomes, and Peculiarities

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dc.contributor.authorKaplan, Muhammet Ali
dc.contributor.authorKarhan, Oğur
dc.contributor.authorUrakçı, Zuhat
dc.contributor.authorEbınc, Senar
dc.contributor.authorAkdeniz, Nadiye
dc.contributor.authorSezgin, Yasin
dc.contributor.authorNacir, Mustafa
dc.date.accessioned2024-04-24T19:11:48Z
dc.date.available2024-04-24T19:11:48Z
dc.date.issued2020
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjective: We aimed to explore different features of rarely seen breast cancer (BC) subtypes, including their stage, molecularsubtypes, treatment choices, and prognosis. Material and Methods: We retrospectively screened patients who were diagnosed with BC inour hospital between July 2010 and June 2018. A total of 97 patients who had micropapillary, cribriform, mucinous, papillary, tubular, apocrine, metaplastic, medullary, and myoepithelial subtypes of BC were finally included in the current study.Results: Ninety-four (96.9%) patients were females. Patients with cribriform and mucinous subtypes were in the younger median age of 41 and 45 years, respectively, whereaspapillary cases were reported in the oldest median age (64.5 years). Lymph node and TNM stages showed a statistical difference between thesubtypes (p=0.029 and p=0.008, respectively). Most of the cribriform (60%), metaplastic (66.7%), and papillary (70%) cases were diagnosedwithout lymph node involvement. Apocrine (79%) and micropapillary (75%) tumors mostly presented with nodal involvement. Whilemedullary (75%), tubular (66.7%), and cribriform (66.7%) carcinomas were more likely to be diagnosed at stage II, micropapillary (70.8%),and apocrine (62.5%) carcinomas were mostly diagnosed at stage III. Mucinous, tubular, and cribriform tumors were noticed in the luminalgroup. Medullary, metaplastic, apocrine, and papillary tumors included triple-negative subgroups. HER2-enriched tumors included apocrine(62.5%), medullary (50%), and micropapillary (25%) subtypes. Disease-free survival and overall survival of the patients showed marginal statistical significance according to tumor subtypes (p=0.086, p=0.085, respectively). Conclusion: In this study, we investigated important features, clinical behavior, management, and outcomes of several rare BC subtypes. We opine that the current study may prove instrumental andinformative for both daily clinical practice and future studies.en_US
dc.identifier.doi10.37047/jos.2020-78231
dc.identifier.endpage172en_US
dc.identifier.issn2651-4532
dc.identifier.issue3en_US
dc.identifier.startpage164en_US
dc.identifier.trdizinid423352
dc.identifier.urihttps://doi.org/10.37047/jos.2020-78231
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/423352
dc.identifier.urihttps://hdl.handle.net/11468/28203
dc.identifier.volume6en_US
dc.indekslendigikaynakTR-Dizin
dc.language.isoenen_US
dc.relation.ispartofJournal of oncological sciences
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleRare Breast Cancer Types: A Study About Characteristics, Outcomes, and Peculiaritiesen_US
dc.titleRare Breast Cancer Types: A Study About Characteristics, Outcomes, and Peculiarities
dc.typeArticleen_US

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